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    Rnps1 ribonucleic acid binding protein S1 [ Mus musculus (house mouse) ]

    Gene ID: 19826, updated on 9-Sep-2018

    Summary

    Official Symbol
    Rnps1provided by MGI
    Official Full Name
    ribonucleic acid binding protein S1provided by MGI
    Primary source
    MGI:MGI:97960
    See related
    Ensembl:ENSMUSG00000034681
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 88.5), CNS E14 (RPKM 86.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rnps1 in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (24414642..24425898)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (24551620..24562843)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family A (ABC1), member 17 Neighboring gene ATP-binding cassette, sub-family A (ABC1), member 3 Neighboring gene RIKEN cDNA D330041H03 gene Neighboring gene enoyl-Coenzyme A delta isomerase 1 Neighboring gene deoxyribonuclease 1-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of alternative mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    ASAP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ASAP complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RNA-binding protein with serine-rich domain 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080127.1NP_001073596.1  RNA-binding protein with serine-rich domain 1 isoform 1

      See identical proteins and their annotated locations for NP_001073596.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an internal exon in the 5' UTR, compared to variant 1. Variants 1, 2 and 4 encode the same isoform (1).
      Source sequence(s)
      AK151150, BX526195, CJ058744
      Consensus CDS
      CCDS37488.1
      UniProtKB/Swiss-Prot
      Q99M28
      Related
      ENSMUSP00000085867.5, ENSMUST00000088512.11
      Conserved Domains (1) summary
      cd12365
      Location:163236
      RRM_RNPS1; RNA recognition motif in RNA-binding protein with serine-rich domain 1 (RNPS1) and similar proteins
    2. NM_001080128.1NP_001073597.1  RNA-binding protein with serine-rich domain 1 isoform 2

      See identical proteins and their annotated locations for NP_001073597.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two consecutive exons in the 5' region, which results in an alternate translation start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK165905, BX526195, BY013195
      Consensus CDS
      CCDS37487.1
      UniProtKB/Swiss-Prot
      Q99M28
      Related
      ENSMUSP00000111028.1, ENSMUST00000115371.7
      Conserved Domains (1) summary
      cd12365
      Location:140213
      RRM_RNPS1; RNA recognition motif in RNA-binding protein with serine-rich domain 1 (RNPS1) and similar proteins
    3. NM_001357626.1NP_001344555.1  RNA-binding protein with serine-rich domain 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 4 encode the same isoform (1).
      Source sequence(s)
      AC154237, BQ174147
      Conserved Domains (1) summary
      cd12365
      Location:163236
      RRM_RNPS1; RNA recognition motif in RNA-binding protein with serine-rich domain 1 (RNPS1) and similar proteins
    4. NM_009070.2NP_033096.2  RNA-binding protein with serine-rich domain 1 isoform 1

      See identical proteins and their annotated locations for NP_033096.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1, 2 and 4 encode the same isoform (1).
      Source sequence(s)
      AK151150, BB868062, BX526195
      Consensus CDS
      CCDS37488.1
      UniProtKB/Swiss-Prot
      Q99M28
      Related
      ENSMUSP00000126345.1, ENSMUST00000163717.1
      Conserved Domains (1) summary
      cd12365
      Location:163236
      RRM_RNPS1; RNA recognition motif in RNA-binding protein with serine-rich domain 1 (RNPS1) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      24414642..24425898
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317362.1XP_017172851.1  RNA-binding protein with serine-rich domain 1 isoform X1

      UniProtKB/Swiss-Prot
      Q99M28
      Conserved Domains (1) summary
      cd12365
      Location:163236
      RRM_RNPS1; RNA recognition motif in RNA-binding protein with serine-rich domain 1 (RNPS1) and similar proteins
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