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    Uri1 URI1, prefoldin-like chaperone [ Mus musculus (house mouse) ]

    Gene ID: 19777, updated on 23-Jun-2021

    Summary

    Official Symbol
    Uri1provided by MGI
    Official Full Name
    URI1, prefoldin-like chaperoneprovided by MGI
    Primary source
    MGI:MGI:1342294
    See related
    Ensembl:ENSMUSG00000030421
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    R; NN; Rmp; NNX3; C80913
    Expression
    Ubiquitous expression in testis adult (RPKM 10.9), bladder adult (RPKM 10.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Uri1 in Genome Data Viewer
    Location:
    7; 7 B3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (37659417..37722989, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (37959992..38023564, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (38745011..38804571, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 536 Neighboring gene RIKEN cDNA 4930505M18 gene Neighboring gene predicted gene, 22302 Neighboring gene predicted gene, 30684 Neighboring gene predicted gene, 30771 Neighboring gene cyclin E1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables phosphoprotein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    unconventional prefoldin RPB5 interactor
    Names
    RNA polymerase II subunit 5-mediating protein
    RPB5-mediating protein
    protein phosphatase 1 regulatory subunit 19

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011274.5NP_035404.4  unconventional prefoldin RPB5 interactor

      See identical proteins and their annotated locations for NP_035404.4

      Status: VALIDATED

      Source sequence(s)
      AK133383, AK166566, BE633468, BY073657
      Consensus CDS
      CCDS21157.1
      UniProtKB/Swiss-Prot
      Q3TLD5
      Related
      ENSMUSP00000082646.5, ENSMUST00000085513.6
      Conserved Domains (1) summary
      cl09111
      Location:36145
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      37659417..37722989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539676.3XP_006539739.2  unconventional prefoldin RPB5 interactor isoform X1

      Related
      ENSMUSP00000145738.2, ENSMUST00000206581.2
      Conserved Domains (1) summary
      cl09111
      Location:48150
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    2. XM_006539677.4XP_006539740.1  unconventional prefoldin RPB5 interactor isoform X2

      Conserved Domains (1) summary
      cl09111
      Location:899
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    3. XM_006539678.5XP_006539741.1  unconventional prefoldin RPB5 interactor isoform X3

      See identical proteins and their annotated locations for XP_006539741.1

      UniProtKB/Swiss-Prot
      Q3TLD5
      Conserved Domains (1) summary
      cl09111
      Location:171
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
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