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    Xpr1 xenotropic and polytropic retrovirus receptor 1 [ Mus musculus (house mouse) ]

    Gene ID: 19775, updated on 2-Aug-2021

    Summary

    Official Symbol
    Xpr1provided by MGI
    Official Full Name
    xenotropic and polytropic retrovirus receptor 1provided by MGI
    Primary source
    MGI:MGI:97932
    See related
    Ensembl:ENSMUSG00000026469
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    XR; Rmc; Sxv; Syg; Rmc-; Rmc1; Syg1; Rmc-1
    Expression
    Broad expression in whole brain E14.5 (RPKM 29.3), CNS E18 (RPKM 27.0) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Xpr1 in Genome Data Viewer
    Location:
    1 G3; 1 66.49 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (155151403..155293190, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (155275657..155417444, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (157122787..157264574, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene syntaxin 6 Neighboring gene high mobility group protein B3 pseudogene Neighboring gene cDNA sequence BC034090 Neighboring gene predicted gene, 31102 Neighboring gene predicted gene, 17974 Neighboring gene predicted gene, 31713 Neighboring gene predicted gene, 31772

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (1)  1 citation
    • Gene trapped (1) 
    • Targeted (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables efflux transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables inositol hexakisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables inositol hexakisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphate ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables phosphate ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables virus receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables virus receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular phosphate ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to phosphate starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in phosphate ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phosphate ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within response to virus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within response to virus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intrinsic component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    xenotropic and polytropic retrovirus receptor 1
    Names
    receptor for MCF virus 1
    suppressor of yeast G<a> deletion
    susceptibility to xenotropic virus
    xenotropic and polytropic murine leukemia virus receptor
    xenotropic and polytropic retrovirus receptor 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011273.2NP_035403.1  xenotropic and polytropic retrovirus receptor 1

      See identical proteins and their annotated locations for NP_035403.1

      Status: VALIDATED

      Source sequence(s)
      AC110268, AF114753, AF198104, BY122762
      Consensus CDS
      CCDS15384.1
      UniProtKB/Swiss-Prot
      Q9Z0U0
      Related
      ENSMUSP00000027741.6, ENSMUST00000027741.12
      Conserved Domains (3) summary
      cd14477
      Location:2165
      SPX_XPR1_like; SPX domain of the xenotropic and polytropic retrovirus receptor 1 (XPR1) and related proteins
      pfam03105
      Location:3169
      SPX; SPX domain
      pfam03124
      Location:286616
      EXS; EXS family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      155151403..155293190 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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