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    Rgn regucalcin [ Mus musculus (house mouse) ]

    Gene ID: 19733, updated on 14-Sep-2021

    Summary

    Official Symbol
    Rgnprovided by MGI
    Official Full Name
    regucalcinprovided by MGI
    Primary source
    MGI:MGI:108024
    See related
    Ensembl:ENSMUSG00000023070
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GNL; SMP; SMP30; AI265316
    Expression
    Biased expression in liver E18 (RPKM 208.8), liver adult (RPKM 124.7) and 2 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rgn in Genome Data Viewer
    Location:
    X; X A1.3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (20416005..20428328)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (20549766..20562089)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (20126944..20139213)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene jade family PHD finger 3 Neighboring gene ubiquitin-like modifier activating enzyme 3 pseudogene Neighboring gene upregulated during skeletal muscle growth 5 pseudogene Neighboring gene predicted gene, 23628

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables enzyme regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables gluconolactonase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables gluconolactonase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables gluconolactonase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in L-ascorbic acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in L-ascorbic acid biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular calcium ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of RNA biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of bone development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of calcium-dependent ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cyclic-nucleotide phosphodiesterase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of epithelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of leucine-tRNA ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of nitric oxide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of phosphoprotein phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of ATPase-coupled calcium transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of dUTP diphosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of fatty acid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of glucose metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of proteolysis involved in cellular protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of superoxide dismutase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of triglyceride biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of calcium-mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    regucalcin
    Names
    RC
    SMP-30
    gluconolactonase
    senescence marker protein 30
    NP_033086.1
    XP_006527635.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009060.2NP_033086.1  regucalcin

      See identical proteins and their annotated locations for NP_033086.1

      Status: PROVISIONAL

      Source sequence(s)
      AL672073
      Consensus CDS
      CCDS30043.1
      UniProtKB/Swiss-Prot
      Q64374
      Related
      ENSMUSP00000023832.7, ENSMUST00000023832.7
      Conserved Domains (1) summary
      pfam08450
      Location:16264
      SGL; SMP-30/Gluconolaconase/LRE-like region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      20416005..20428328
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527572.3XP_006527635.1  regucalcin isoform X1

      See identical proteins and their annotated locations for XP_006527635.1

      UniProtKB/Swiss-Prot
      Q64374
      Conserved Domains (1) summary
      pfam08450
      Location:16264
      SGL; SMP-30/Gluconolaconase/LRE-like region
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