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    Rad23b RAD23 homolog B, nucleotide excision repair protein [ Mus musculus (house mouse) ]

    Gene ID: 19359, updated on 6-Nov-2018

    Summary

    Official Symbol
    Rad23bprovided by MGI
    Official Full Name
    RAD23 homolog B, nucleotide excision repair proteinprovided by MGI
    Primary source
    MGI:MGI:105128
    See related
    Ensembl:ENSMUSG00000028426 Vega:OTTMUSG00000007227
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p58; HR23B; mHR23B; AV001138; 0610007D13Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 58.0), CNS E11.5 (RPKM 42.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rad23b in Genome Data Viewer
    Location:
    4; 4 B3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (55350042..55392237)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (55362914..55405109)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene 12512 Neighboring gene predicted gene, 42290 Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene predicted gene, 34290

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    polyubiquitin modification-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    polyubiquitin modification-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    proteasome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleotide-excision repair ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide-excision repair, DNA damage recognition ISO
    Inferred from Sequence Orthology
    more info
     
    proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    XPC complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    proteasome complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    UV excision repair protein RAD23 homolog B
    Names
    RAD23b homolog
    XP-C repair-complementing complex 58 kDa protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009011.4NP_033037.2  UV excision repair protein RAD23 homolog B

      See identical proteins and their annotated locations for NP_033037.2

      Status: VALIDATED

      Source sequence(s)
      AK142280, AK150089, BE989853, BY140385
      Consensus CDS
      CCDS18194.1
      UniProtKB/Swiss-Prot
      P54728
      UniProtKB/TrEMBL
      Q3UQN3
      Related
      ENSMUSP00000030134.8, OTTMUSP00000007676, ENSMUST00000030134.8, OTTMUST00000016670
      Conserved Domains (5) summary
      cd01805
      Location:178
      RAD23_N; Ubiquitin-like domain of RAD23
      cd14377
      Location:189228
      UBA1_Rad23; UBA1 domain of Rad23 proteins found in metazoa
      cd14428
      Location:372416
      UBA2_HR23B; UBA2 domain of UV excision repair protein RAD23 homolog B (HR23B) found in vertebrates
      TIGR00601
      Location:1414
      rad23; UV excision repair protein Rad23
      pfam09280
      Location:276331
      XPC-binding; XPC-binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      55350042..55392237
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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