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    Rab22a RAB22A, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 19334, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rab22aprovided by MGI
    Official Full Name
    RAB22A, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:105072
    See related
    Ensembl:ENSMUSG00000027519
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rab; Rab22; AI662177; AW319644; AW550514; 3732413A17Rik; E130120E14Rik
    Expression
    Ubiquitous expression in colon adult (RPKM 24.0), testis adult (RPKM 24.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rab22a in Genome Data Viewer
    Location:
    2 H4; 2 97.26 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (173501638..173543975)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (173659836..173702186)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (173485346..173527683)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 60 Neighboring gene protein phosphatase 4, regulatory subunit 1-like, pseudogene Neighboring gene microRNA 6340 Neighboring gene RIKEN cDNA 1700010B08 gene Neighboring gene vesicle-associated membrane protein, associated protein B and C Neighboring gene adenomatosis polyposis coli down-regulated 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables GTPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of vesicle size ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in phagocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-22A
    Names
    RAB22, member RAS oncogene family
    rab-14
    rab-22
    NP_077756.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024436.3NP_077756.2  ras-related protein Rab-22A

      See identical proteins and their annotated locations for NP_077756.2

      Status: PROVISIONAL

      Source sequence(s)
      AK146594
      Consensus CDS
      CCDS38352.1
      UniProtKB/Swiss-Prot
      P35285
      UniProtKB/TrEMBL
      Q0PD34
      Related
      ENSMUSP00000029024.4, ENSMUST00000029024.10
      Conserved Domains (1) summary
      cd01860
      Location:5167
      Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      173501638..173543975
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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