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    Rab10 RAB10, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 19325, updated on 31-Jan-2019

    Summary

    Official Symbol
    Rab10provided by MGI
    Official Full Name
    RAB10, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:105066
    See related
    Ensembl:ENSMUSG00000020671
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW107754
    Expression
    Ubiquitous expression in CNS E18 (RPKM 55.0), bladder adult (RPKM 47.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rab10 in Genome Data Viewer
    Location:
    12 A1.1; 12 1.71 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (3247428..3309969, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (3247428..3309969, complement)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene NLR family, pyrin domain containing 2 pseudogene Neighboring gene NLR family, pyrin domain containing 5 pseudogene Neighboring gene RAB10, member RAS oncogene family, opposite strand Neighboring gene uncharacterized LOC108167952 Neighboring gene predicted gene, 26520 Neighboring gene RIKEN cDNA I920046F24 gene Neighboring gene kinesin family member 3C

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GDP-dissociation inhibitor binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    myosin V binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Golgi to plasma membrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    Rab protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    antigen processing and presentation ISO
    Inferred from Sequence Orthology
    more info
     
    axonogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to insulin stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to insulin stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    endoplasmic reticulum tubular network organization ISO
    Inferred from Sequence Orthology
    more info
     
    endosomal transport ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of neuroblast polarity ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of protein localization to endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of protein localization to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular protein transport TAS
    Traceable Author Statement
    more info
    PubMed 
    protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein localization to plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vesicle docking involved in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    anchored component of synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cilium ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum tubular network ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endosome ISO
    Inferred from Sequence Orthology
    more info
     
    exocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    insulin-responsive compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    insulin-responsive compartment ISO
    Inferred from Sequence Orthology
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    synaptic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016676.5NP_057885.1  ras-related protein Rab-10

      See identical proteins and their annotated locations for NP_057885.1

      Status: VALIDATED

      Source sequence(s)
      AK028320, BC052735, CJ092612
      Consensus CDS
      CCDS25782.1
      UniProtKB/Swiss-Prot
      P61027
      UniProtKB/TrEMBL
      Q4FJL0
      Related
      ENSMUSP00000021001.8, ENSMUST00000021001.9
      Conserved Domains (1) summary
      cd01867
      Location:7173
      Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      3247428..3309969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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