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    Rab1a RAB1A, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 19324, updated on 5-Sep-2021

    Summary

    Official Symbol
    Rab1aprovided by MGI
    Official Full Name
    RAB1A, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:97842
    See related
    Ensembl:ENSMUSG00000020149
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ra; Gtb; Rab; Ypt; Gtbp; Rab1; Ypt1; Rab-1; mKIAA3012
    Expression
    Ubiquitous expression in placenta adult (RPKM 75.8), liver E18 (RPKM 58.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rab1a in Genome Data Viewer
    Location:
    11 A3.1; 11 12.92 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (20151412..20176856)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (20201412..20226856)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (20101605..20126859)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12031 Neighboring gene predicted gene, 26253 Neighboring gene centrosomal protein 68 Neighboring gene predicted gene, 39604 Neighboring gene ribosomal proteimn L12-ps2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Endonuclease-mediated (1)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in COPII-coated vesicle cargo loading ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in autophagosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in defense response to bacterium ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in growth hormone secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within intracellular protein transport TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in melanosome transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of glycoprotein metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of interleukin-8 production ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in substrate adhesion-dependent cell spreading IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vesicle transport along microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in virion assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in melanosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-1A
    Names
    RAB1, member RAS oncogene family
    YPT1-related protein
    ras-related YPT1 protein
    NP_033022.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008996.4NP_033022.1  ras-related protein Rab-1A

      See identical proteins and their annotated locations for NP_033022.1

      Status: VALIDATED

      Source sequence(s)
      AK034408, AK159425, AK167150, BY283776, CB723426
      Consensus CDS
      CCDS36115.1
      UniProtKB/Swiss-Prot
      P62821
      UniProtKB/TrEMBL
      Q0PD67
      Related
      ENSMUSP00000020358.6, ENSMUST00000020358.12
      Conserved Domains (1) summary
      cd01869
      Location:10175
      Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      20151412..20176856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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