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    Arhgdia Rho GDP dissociation inhibitor (GDI) alpha [ Mus musculus (house mouse) ]

    Gene ID: 192662, updated on 22-Aug-2021

    Summary

    Official Symbol
    Arhgdiaprovided by MGI
    Official Full Name
    Rho GDP dissociation inhibitor (GDI) alphaprovided by MGI
    Primary source
    MGI:MGI:2178103
    See related
    Ensembl:ENSMUSG00000025132
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rho-; Gdi-1; RhoDGI; Rho-GDI; RhoGDI-1; rho GDI 1; 5330430M07Rik; Rho GDI alpha; rho-GDI alpha
    Expression
    Ubiquitous expression in duodenum adult (RPKM 291.0), lung adult (RPKM 246.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Arhgdia in Genome Data Viewer
    Location:
    11; 11 E2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (120468925..120472450, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (120578099..120581624, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (120438549..120442934, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1, regulatory subunit 27 Neighboring gene prolyl 4-hydroxylase, beta polypeptide Neighboring gene Aly/REF export factor Neighboring gene anaphase promoting complex subunit 11 Neighboring gene neuropeptide B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC7904, MGC101921

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables Hsp90 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables Rho GDP-dissociation inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables Rho GDP-dissociation inhibitor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables fatty acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in immunological synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    rho GDP-dissociation inhibitor 1
    Names
    Rho GDIalpha

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363425.1NP_001350354.1  rho GDP-dissociation inhibitor 1

      Status: VALIDATED

      Source sequence(s)
      AK077343, AL663030
      Consensus CDS
      CCDS25743.1
      Related
      ENSMUSP00000063714.6, ENSMUST00000067936.6
      Conserved Domains (1) summary
      pfam02115
      Location:11201
      Rho_GDI; RHO protein GDP dissociation inhibitor
    2. NM_133796.8NP_598557.3  rho GDP-dissociation inhibitor 1

      See identical proteins and their annotated locations for NP_598557.3

      Status: VALIDATED

      Source sequence(s)
      AK165241, AL663030, CJ091996
      Consensus CDS
      CCDS25743.1
      UniProtKB/Swiss-Prot
      Q99PT1
      Related
      ENSMUSP00000101803.4, ENSMUST00000106197.10
      Conserved Domains (1) summary
      pfam02115
      Location:11201
      Rho_GDI; RHO protein GDP dissociation inhibitor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      120468925..120472450 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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