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    Rfpl4 ret finger protein-like 4 [ Mus musculus (house mouse) ]

    Gene ID: 192658, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rfpl4provided by MGI
    Official Full Name
    ret finger protein-like 4provided by MGI
    Primary source
    MGI:MGI:2149590
    See related
    Ensembl:ENSMUSG00000035191
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rfpl4a; D7Ertd486; D7Ertd486e
    Expression
    Restricted expression toward ovary adult (RPKM 1.2) See more
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    Genomic context

    See Rfpl4 in Genome Data Viewer
    Location:
    7 A1; 7 2.96 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (5112786..5119910, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (5109787..5116911, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (5061389..5068513, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 Neighboring gene epsin 1 Neighboring gene RAS-like, family 2, locus 9 Neighboring gene predicted gene, 47692

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    NOT located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145013.1NP_001138485.1  ret finger protein-like 4A

      See identical proteins and their annotated locations for NP_001138485.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK136022, AK139569, BC069834
      Consensus CDS
      CCDS20759.1
      UniProtKB/Swiss-Prot
      Q8VH31
      Related
      ENSMUSP00000136497.2, ENSMUST00000179971.8
      Conserved Domains (3) summary
      pfam11002
      Location:5495
      RDM; RFPL defining motif (RDM)
      cd15821
      Location:94272
      SPRY_PRY_RFPL; Ret finger protein-like (RFPL), includes RFP1, 2, 3, 4
      cl17238
      Location:1152
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    2. NM_138954.3NP_620404.1  ret finger protein-like 4A

      See identical proteins and their annotated locations for NP_620404.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK136022, AK139569, AY070253
      Consensus CDS
      CCDS20759.1
      UniProtKB/Swiss-Prot
      Q8VH31
      Related
      ENSMUSP00000039519.8, ENSMUST00000045215.9
      Conserved Domains (3) summary
      pfam11002
      Location:5495
      RDM; RFPL defining motif (RDM)
      cd15821
      Location:94272
      SPRY_PRY_RFPL; Ret finger protein-like (RFPL), includes RFP1, 2, 3, 4
      cl17238
      Location:1152
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      5112786..5119910 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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