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    Tmsb10 thymosin, beta 10 [ Mus musculus (house mouse) ]

    Gene ID: 19240, updated on 20-Jul-2021

    Summary

    Official Symbol
    Tmsb10provided by MGI
    Official Full Name
    thymosin, beta 10provided by MGI
    Primary source
    MGI:MGI:109146
    See related
    Ensembl:ENSMUSG00000079523
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tb10; Ptmb1; Ptmb10
    Expression
    Biased expression in CNS E18 (RPKM 401.3), CNS E14 (RPKM 333.4) and 14 other tissues See more
    Orthologs
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    Genomic context

    See Tmsb10 in Genome Data Viewer
    Location:
    6; 6 C1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (72934330..72935731, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (72957347..72958748, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (72907341..72908742, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene potassium channel modulatory factor 1 Neighboring gene transfer RNA serine (anticodon GCU) Neighboring gene mediator complex subunit 29 pseudogene Neighboring gene predicted gene, 31547

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin monomer binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables actin monomer binding TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in sequestering of actin monomers IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IC
    Inferred by Curator
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039392.2NP_001034481.1  thymosin beta-10

      See identical proteins and their annotated locations for NP_001034481.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AK003178, CJ042349, CJ042420
      Consensus CDS
      CCDS39519.1
      UniProtKB/Swiss-Prot
      Q6ZWY8
      UniProtKB/TrEMBL
      A6H6H4
      Related
      ENSMUSP00000109683.2, ENSMUST00000114049.2
      Conserved Domains (1) summary
      pfam01290
      Location:341
      Thymosin; Thymosin beta-4 family
    2. NM_001190327.1NP_001177256.1  thymosin beta-10

      See identical proteins and their annotated locations for NP_001177256.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC153842, AK003178
      Consensus CDS
      CCDS39519.1
      UniProtKB/Swiss-Prot
      Q6ZWY8
      UniProtKB/TrEMBL
      A6H6H4
      Related
      ENSMUSP00000109682.2, ENSMUST00000114048.2
      Conserved Domains (1) summary
      pfam01290
      Location:341
      Thymosin; Thymosin beta-4 family
    3. NM_025284.4NP_079560.1  thymosin beta-10

      See identical proteins and their annotated locations for NP_079560.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC153842, AK003178
      Consensus CDS
      CCDS39519.1
      UniProtKB/Swiss-Prot
      Q6ZWY8
      UniProtKB/TrEMBL
      A6H6H4
      Related
      ENSMUSP00000109684.2, ENSMUST00000114050.8
      Conserved Domains (1) summary
      pfam01290
      Location:341
      Thymosin; Thymosin beta-4 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      72934330..72935731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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