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    Psmb1 proteasome (prosome, macropain) subunit, beta type 1 [ Mus musculus (house mouse) ]

    Gene ID: 19170, updated on 23-Jun-2021

    Summary

    Official Symbol
    Psmb1provided by MGI
    Official Full Name
    proteasome (prosome, macropain) subunit, beta type 1provided by MGI
    Primary source
    MGI:MGI:104884
    See related
    Ensembl:ENSMUSG00000014769
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lmp; Lmpc5; C81484; AA409053
    Expression
    Ubiquitous expression in placenta adult (RPKM 121.4), large intestine adult (RPKM 112.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Psmb1 in Genome Data Viewer
    Location:
    17 A2; 17 8.95 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (15695983..15718538, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (15475721..15498276, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (15612685..15635240, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118568318 Neighboring gene delta like canonical Notch ligand 1 Neighboring gene family with sequence similarity 120, member B Neighboring gene predicted gene, 49668 Neighboring gene TATA box binding protein Neighboring gene programmed cell death 2 Neighboring gene zinc finger protein 91 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables threonine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteasomal protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in proteolysis involved in cellular protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of proteasome complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of proteasome core complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of proteasome core complex, beta-subunit complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    proteasome subunit beta type-1
    Names
    component C5 of proteasome
    macropain subunit C5
    multicatalytic endopeptidase complex subunit C5
    proteasome beta-subunit C5
    proteasome component C5
    proteasome gamma chain
    proteasome subunit C5
    NP_035315.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011185.3NP_035315.1  proteasome subunit beta type-1

      See identical proteins and their annotated locations for NP_035315.1

      Status: PROVISIONAL

      Source sequence(s)
      AK132161
      Consensus CDS
      CCDS28411.1
      UniProtKB/Swiss-Prot
      O09061
      UniProtKB/TrEMBL
      Q6RI64
      Related
      ENSMUSP00000014913.9, ENSMUST00000014913.11
      Conserved Domains (2) summary
      COG0638
      Location:18240
      PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
      cd03757
      Location:29240
      proteasome_beta_type_1; proteasome beta type-1 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      15695983..15718538 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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