Format

Send to:

Choose Destination
    • Showing Current items.

    Prpf4b pre-mRNA processing factor 4B [ Mus musculus (house mouse) ]

    Gene ID: 19134, updated on 5-Sep-2021

    Summary

    Official Symbol
    Prpf4bprovided by MGI
    Official Full Name
    pre-mRNA processing factor 4Bprovided by MGI
    Primary source
    MGI:MGI:109584
    See related
    Ensembl:ENSMUSG00000021413
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P; Pr; Prp4; Prpk; Prp4k; cbp143; 2610037H07
    Expression
    Broad expression in CNS E11.5 (RPKM 19.1), limb E14.5 (RPKM 16.8) and 22 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Prpf4b in Genome Data Viewer
    Location:
    13; 13 A3.3
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (35058803..35090047)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (34874820..34906064)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (34967363..34994747)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm180 Neighboring gene ribosomal protein S4, X-linked pseudogene Neighboring gene predicted gene, 36839 Neighboring gene family with sequence similarity 217, member A Neighboring gene RIKEN cDNA 4933417A18 gene Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC5960

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA cis splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein kinase PRP4 homolog
    Names
    PRP4 pre-mRNA processing factor 4 homolog B
    PRP4 pre-mRNA-processing factor 4 homolog
    pre-mRNA protein kinase
    NP_038858.2
    XP_006516645.1
    XP_006516647.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013830.3NP_038858.2  serine/threonine-protein kinase PRP4 homolog

      See identical proteins and their annotated locations for NP_038858.2

      Status: VALIDATED

      Source sequence(s)
      AC124537, AC132344
      Consensus CDS
      CCDS26448.1
      UniProtKB/Swiss-Prot
      Q61136
      UniProtKB/TrEMBL
      Q8C5G1
      Related
      ENSMUSP00000077019.4, ENSMUST00000077853.5
      Conserved Domains (2) summary
      PTZ00449
      Location:171393
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd14135
      Location:6861003
      STKc_PRP4; Catalytic domain of the Serine/Threonine Kinase, Pre-mRNA-Processing factor 4

    RNA

    1. NR_165078.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124537, AC132344
    2. NR_165079.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124537, AC132344

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      35058803..35090047
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516584.4XP_006516647.1  serine/threonine-protein kinase PRP4 homolog isoform X2

      Conserved Domains (2) summary
      PTZ00449
      Location:171393
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cl21453
      Location:686860
      PKc_like; Protein Kinases, catalytic domain
    2. XM_006516582.4XP_006516645.1  serine/threonine-protein kinase PRP4 homolog isoform X1

      Conserved Domains (2) summary
      PTZ00449
      Location:171393
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cl21453
      Location:686860
      PKc_like; Protein Kinases, catalytic domain

    RNA

    1. XR_004937977.1 RNA Sequence

    2. XR_004937978.1 RNA Sequence

    3. XR_004937979.1 RNA Sequence

    4. XR_004937980.1 RNA Sequence

    5. XR_004937976.1 RNA Sequence

    6. XR_004937974.1 RNA Sequence

    7. XR_004937975.1 RNA Sequence

    8. XR_004937968.1 RNA Sequence

    9. XR_004937969.1 RNA Sequence

    10. XR_004937970.1 RNA Sequence

    11. XR_004937971.1 RNA Sequence

    12. XR_004937972.1 RNA Sequence

    13. XR_004937973.1 RNA Sequence

    14. XR_004937966.1 RNA Sequence

    15. XR_004937967.1 RNA Sequence

    16. XR_004937946.1 RNA Sequence

    17. XR_004937950.1 RNA Sequence

    18. XR_004937956.1 RNA Sequence

    19. XR_004937945.1 RNA Sequence

    20. XR_004937949.1 RNA Sequence

    21. XR_004937954.1 RNA Sequence

    22. XR_004937958.1 RNA Sequence

    23. XR_004937952.1 RNA Sequence

    24. XR_004937953.1 RNA Sequence

    25. XR_004937947.1 RNA Sequence

    26. XR_004937955.1 RNA Sequence

    27. XR_004937962.1 RNA Sequence

    28. XR_004937948.1 RNA Sequence

    29. XR_004937951.1 RNA Sequence

    30. XR_004937957.1 RNA Sequence

    31. XR_004937960.1 RNA Sequence

    32. XR_004937959.1 RNA Sequence

    33. XR_004937961.1 RNA Sequence

    34. XR_004937963.1 RNA Sequence

    35. XR_004937964.1 RNA Sequence

    36. XR_004937965.1 RNA Sequence

    Support Center