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    Ppfibp2 PTPRF interacting protein, binding protein 2 (liprin beta 2) [ Mus musculus (house mouse) ]

    Gene ID: 19024, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ppfibp2provided by MGI
    Official Full Name
    PTPRF interacting protein, binding protein 2 (liprin beta 2)provided by MGI
    Primary source
    MGI:MGI:894649
    See related
    Ensembl:ENSMUSG00000036528
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccl; Cclp1
    Expression
    Broad expression in bladder adult (RPKM 12.0), placenta adult (RPKM 5.7) and 23 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ppfibp2 in Genome Data Viewer
    Location:
    7; 7 E3
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (107192608..107347790)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (107595047..107748583)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (114738565..114892097)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene synaptotagmin IX Neighboring gene olfactomedin-like 1 Neighboring gene cytochrome b5 reductase 2 Neighboring gene ovochymase 2 Neighboring gene olfactory receptor 467

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Clone Names

    • MGC117695

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in neuromuscular junction development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in presynaptic active zone IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    liprin-beta-2
    Names
    PTPRF-interacting protein-binding protein 2
    coiled-coil-like protein 1
    protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2
    protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163557.1NP_001157029.1  liprin-beta-2 isoform 2

      See identical proteins and their annotated locations for NP_001157029.1

      Status: VALIDATED

      Source sequence(s)
      BC100346
      Consensus CDS
      CCDS52356.1
      UniProtKB/Swiss-Prot
      O35711
      Related
      ENSMUSP00000095738.4, ENSMUST00000098134.5
      Conserved Domains (5) summary
      cd09563
      Location:550613
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:624686
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:709780
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      smart00454
      Location:550614
      SAM; Sterile alpha motif
      pfam01519
      Location:110161
      DUF16; Protein of unknown function DUF16
    2. NM_001357436.1NP_001344365.1  liprin-beta-2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL513346
      Conserved Domains (4) summary
      cd09563
      Location:484547
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:558620
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:643714
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      cl25732
      Location:28231
      SMC_N; RecF/RecN/SMC N terminal domain
    3. NM_001357437.1NP_001344366.1  liprin-beta-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL513346
      Conserved Domains (4) summary
      cd09563
      Location:473536
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:547609
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:632703
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      cl25732
      Location:28231
      SMC_N; RecF/RecN/SMC N terminal domain
    4. NM_001357438.1NP_001344367.1  liprin-beta-2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL513346
      Conserved Domains (4) summary
      cd09563
      Location:400463
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:474536
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:559630
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      cl25732
      Location:16152
      SMC_N; RecF/RecN/SMC N terminal domain
    5. NM_008905.2NP_032931.2  liprin-beta-2 isoform 1

      See identical proteins and their annotated locations for NP_032931.2

      Status: VALIDATED

      Source sequence(s)
      AW045216, BB627669, CJ075536, U79024
      Consensus CDS
      CCDS21691.1
      UniProtKB/Swiss-Prot
      O35711
      UniProtKB/TrEMBL
      G3X957
      Related
      ENSMUSP00000042574.8, ENSMUST00000040056.15
      Conserved Domains (5) summary
      cd09563
      Location:561624
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:635697
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:720791
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:105308
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd22296
      Location:419464
      CBD_TRPV5_C; C-terminal CaM binding domain found in transient receptor potential cation channel subfamily V member 5 (TRPV5) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      107192608..107347790
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152792.1XP_036008685.1  liprin-beta-2 isoform X3

      Conserved Domains (5) summary
      cd09563
      Location:561624
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:635697
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:720791
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:105308
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd22296
      Location:419464
      CBD_TRPV5_C; C-terminal CaM binding domain found in transient receptor potential cation channel subfamily V member 5 (TRPV5) and similar proteins
    2. XM_036152793.1XP_036008686.1  liprin-beta-2 isoform X4

      Conserved Domains (4) summary
      cd09563
      Location:550613
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:624686
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:709780
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:105308
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    3. XM_030242235.1XP_030098095.1  liprin-beta-2 isoform X10

      Conserved Domains (4) summary
      cd09563
      Location:597660
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:671733
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:756827
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:141344
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    4. XM_006507443.3XP_006507506.1  liprin-beta-2 isoform X1

      Conserved Domains (4) summary
      cd09563
      Location:597660
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:671733
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:756827
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:141344
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    5. XM_006507444.3XP_006507507.1  liprin-beta-2 isoform X2

      Conserved Domains (4) summary
      cd09563
      Location:586649
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:660722
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:745816
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:141344
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    6. XM_006507453.1XP_006507516.1  liprin-beta-2 isoform X9

      See identical proteins and their annotated locations for XP_006507516.1

      Conserved Domains (5) summary
      cd09563
      Location:403466
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:477539
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:562633
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:8144
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd22296
      Location:261306
      CBD_TRPV5_C; C-terminal CaM binding domain found in transient receptor potential cation channel subfamily V member 5 (TRPV5) and similar proteins
    7. XM_006507454.1XP_006507517.1  liprin-beta-2 isoform X9

      See identical proteins and their annotated locations for XP_006507517.1

      Conserved Domains (5) summary
      cd09563
      Location:403466
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:477539
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:562633
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:8144
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd22296
      Location:261306
      CBD_TRPV5_C; C-terminal CaM binding domain found in transient receptor potential cation channel subfamily V member 5 (TRPV5) and similar proteins
    8. XM_036152795.1XP_036008688.1  liprin-beta-2 isoform X9

      Conserved Domains (5) summary
      cd09563
      Location:403466
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:477539
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:562633
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:8144
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd22296
      Location:261306
      CBD_TRPV5_C; C-terminal CaM binding domain found in transient receptor potential cation channel subfamily V member 5 (TRPV5) and similar proteins
    9. XM_036152794.1XP_036008687.1  liprin-beta-2 isoform X6

      Conserved Domains (4) summary
      cd09563
      Location:473536
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:547609
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:632703
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:28231
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    10. XM_006507446.4XP_006507509.1  liprin-beta-2 isoform X5

      See identical proteins and their annotated locations for XP_006507509.1

      Conserved Domains (4) summary
      cd09563
      Location:481544
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:555617
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:640711
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:25228
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    11. XM_006507452.5XP_006507515.1  liprin-beta-2 isoform X9

      See identical proteins and their annotated locations for XP_006507515.1

      Conserved Domains (5) summary
      cd09563
      Location:403466
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:477539
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:562633
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:8144
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd22296
      Location:261306
      CBD_TRPV5_C; C-terminal CaM binding domain found in transient receptor potential cation channel subfamily V member 5 (TRPV5) and similar proteins
    12. XM_006507455.5XP_006507518.1  liprin-beta-2 isoform X9

      See identical proteins and their annotated locations for XP_006507518.1

      Conserved Domains (5) summary
      cd09563
      Location:403466
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:477539
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:562633
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:8144
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd22296
      Location:261306
      CBD_TRPV5_C; C-terminal CaM binding domain found in transient receptor potential cation channel subfamily V member 5 (TRPV5) and similar proteins
    13. XM_006507448.4XP_006507511.1  liprin-beta-2 isoform X7

      See identical proteins and their annotated locations for XP_006507511.1

      Conserved Domains (4) summary
      cd09563
      Location:411474
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:485547
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:570641
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:16152
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    14. XM_006507449.4XP_006507512.1  liprin-beta-2 isoform X7

      See identical proteins and their annotated locations for XP_006507512.1

      Conserved Domains (4) summary
      cd09563
      Location:411474
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:485547
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:570641
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:16152
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    15. XM_006507450.4XP_006507513.1  liprin-beta-2 isoform X7

      See identical proteins and their annotated locations for XP_006507513.1

      Conserved Domains (4) summary
      cd09563
      Location:411474
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:485547
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:570641
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      TIGR02168
      Location:16152
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    16. XM_006507451.1XP_006507514.1  liprin-beta-2 isoform X8

      Conserved Domains (4) summary
      cd09563
      Location:404467
      SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
      cd09566
      Location:478540
      SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
      cd09569
      Location:563634
      SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
      PRK03918
      Location:46197
      PRK03918; DNA double-strand break repair ATPase Rad50
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