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    Pold2 polymerase (DNA directed), delta 2, regulatory subunit [ Mus musculus (house mouse) ]

    Gene ID: 18972, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pold2provided by MGI
    Official Full Name
    polymerase (DNA directed), delta 2, regulatory subunitprovided by MGI
    Primary source
    MGI:MGI:1097163
    See related
    Ensembl:ENSMUSG00000020471
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p5; p50; po1; 50kD; 50kDa; po1D2
    Expression
    Broad expression in adrenal adult (RPKM 221.0), mammary gland adult (RPKM 85.3) and 22 other tissues See more
    Orthologs
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    Genomic context

    See Pold2 in Genome Data Viewer
    Location:
    11; 11 A1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (5822180..5828256, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (5872180..5878256, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (5772183..5778259, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene phosphoglycerate mutase 2 Neighboring gene polymerase (DNA directed), mu Neighboring gene AE binding protein 1 Neighboring gene predicted gene, 53664 Neighboring gene myosin, light polypeptide 7, regulatory Neighboring gene glucokinase Neighboring gene predicted gene 11967

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in DNA biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in DNA biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in DNA strand elongation involved in DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in DNA-dependent DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of DNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of delta DNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of delta DNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of delta DNA polymerase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of zeta DNA polymerase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DNA polymerase delta subunit 2
    Names
    DNA polymerase delta subunit p50
    NP_001348871.1
    NP_032920.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361942.1NP_001348871.1  DNA polymerase delta subunit 2

      Status: VALIDATED

      Source sequence(s)
      AL627069, AV329456, BM946479, BQ840484, CX565680
      Consensus CDS
      CCDS24407.1
      Conserved Domains (1) summary
      cd07387
      Location:215452
      MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain
    2. NM_008894.2NP_032920.2  DNA polymerase delta subunit 2

      See identical proteins and their annotated locations for NP_032920.2

      Status: VALIDATED

      Source sequence(s)
      BG078511, BM215242, BY093766, BY668936, CB205181
      Consensus CDS
      CCDS24407.1
      UniProtKB/Swiss-Prot
      O35654
      Related
      ENSMUSP00000099986.4, ENSMUST00000102922.10
      Conserved Domains (1) summary
      cd07387
      Location:215452
      MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      5822180..5828256 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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