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    Plxna1 plexin A1 [ Mus musculus (house mouse) ]

    Gene ID: 18844, updated on 23-Jun-2021

    Summary

    Official Symbol
    Plxna1provided by MGI
    Official Full Name
    plexin A1provided by MGI
    Primary source
    MGI:MGI:107685
    See related
    Ensembl:ENSMUSG00000030084
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pl; NOV; Ple; Plxn1; PlexA1; mKIAA4053; 2600013D04Rik
    Expression
    Broad expression in lung adult (RPKM 77.1), ovary adult (RPKM 54.3) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Plxna1 in Genome Data Viewer
    Location:
    6; 6 D1
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (89293295..89339595, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (89316313..89362613, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (89266307..89312607, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm1516 Neighboring gene RIKEN cDNA 4930512J16 gene Neighboring gene predicted gene, 36735 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 6 Neighboring gene predicted gene, 52910 Neighboring gene predicted gene, 46966

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • KIAA4053

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables semaphorin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables semaphorin receptor activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    part_of semaphorin receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    plexin-A1
    Names
    plex 1
    plexin-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008881.2NP_032907.1  plexin-A1 precursor

      See identical proteins and their annotated locations for NP_032907.1

      Status: VALIDATED

      Source sequence(s)
      AK220460, BC138023, CF734847, CJ111942
      Consensus CDS
      CCDS20344.1
      UniProtKB/Swiss-Prot
      P70206
      Related
      ENSMUSP00000131840.2, ENSMUST00000163139.8
      Conserved Domains (7) summary
      cd11271
      Location:36511
      Sema_plexin_A1; The Sema domain, a protein interacting module, of Plexin A1
      cd01179
      Location:9591044
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:862958
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:10461146
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:512554
      PSI; Plexin repeat
      pfam01833
      Location:11481232
      TIG; IPT/TIG domain
      pfam08337
      Location:13161864
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      89293295..89339595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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