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    Pkig protein kinase inhibitor, gamma [ Mus musculus (house mouse) ]

    Gene ID: 18769, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pkigprovided by MGI
    Official Full Name
    protein kinase inhibitor, gammaprovided by MGI
    Primary source
    MGI:MGI:1343086
    See related
    Ensembl:ENSMUSG00000035268
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PKIgamma
    Expression
    Ubiquitous expression in testis adult (RPKM 82.9), heart adult (RPKM 72.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pkig in Genome Data Viewer
    Location:
    2 H3; 2 84.4 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (163500131..163568078)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (163658211..163726158)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (163484122..163551894)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene tocopherol (alpha) transfer protein-like Neighboring gene serine incorporator 3 Neighboring gene RIKEN cDNA 0610039K10 gene Neighboring gene predicted gene 16316 Neighboring gene adenosine deaminase intronic regulatory elements Neighboring gene adenosine deaminase Neighboring gene adenosine deaminase upstream regulatory elements

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    cAMP-dependent protein kinase inhibitor gamma

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039390.2NP_001034479.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

      See identical proteins and their annotated locations for NP_001034479.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
      Source sequence(s)
      AK164716, BY283174, BY617655, CJ051558
      Consensus CDS
      CCDS17014.1
      UniProtKB/Swiss-Prot
      O70139
      UniProtKB/TrEMBL
      Q3TP50
      Related
      ENSMUSP00000096704.3, ENSMUST00000099105.9
      Conserved Domains (1) summary
      pfam02827
      Location:270
      PKI; cAMP-dependent protein kinase inhibitor
    2. NM_001039391.2NP_001034480.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

      See identical proteins and their annotated locations for NP_001034480.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
      Source sequence(s)
      AK164716, BY343638, BY617655, CJ051558
      Consensus CDS
      CCDS17014.1
      UniProtKB/Swiss-Prot
      O70139
      UniProtKB/TrEMBL
      Q3TP50
      Related
      ENSMUSP00000068344.7, ENSMUST00000064703.13
      Conserved Domains (1) summary
      pfam02827
      Location:270
      PKI; cAMP-dependent protein kinase inhibitor
    3. NM_001164053.1NP_001157525.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

      See identical proteins and their annotated locations for NP_001157525.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
      Source sequence(s)
      AK164716, BY240874, BY266193, BY617655
      Consensus CDS
      CCDS17014.1
      UniProtKB/Swiss-Prot
      O70139
      UniProtKB/TrEMBL
      Q3TP50
      Related
      ENSMUSP00000120145.2, ENSMUST00000126182.8
      Conserved Domains (1) summary
      pfam02827
      Location:270
      PKI; cAMP-dependent protein kinase inhibitor
    4. NM_001164055.1NP_001157527.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

      See identical proteins and their annotated locations for NP_001157527.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
      Source sequence(s)
      AL591490
      Consensus CDS
      CCDS17014.1
      UniProtKB/Swiss-Prot
      O70139
      UniProtKB/TrEMBL
      Q3TP50
      Related
      ENSMUSP00000126223.2, ENSMUST00000164399.8
      Conserved Domains (1) summary
      pfam02827
      Location:270
      PKI; cAMP-dependent protein kinase inhibitor
    5. NM_001277096.1NP_001264025.1  cAMP-dependent protein kinase inhibitor gamma isoform 2

      See identical proteins and their annotated locations for NP_001264025.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and uses an alternate in-frame splice site, compared to variant 4. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AL591490
      Conserved Domains (1) summary
      pfam02827
      Location:269
      PKI; cAMP-dependent protein kinase inhibitor
    6. NM_011106.2NP_035236.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

      See identical proteins and their annotated locations for NP_035236.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents use of an alternate promoter and 5' UTR, compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
      Source sequence(s)
      AV342749, U97170, W75470
      Consensus CDS
      CCDS17014.1
      UniProtKB/Swiss-Prot
      O70139
      UniProtKB/TrEMBL
      Q3TP50
      Related
      ENSMUSP00000105027.3, ENSMUST00000109400.3
      Conserved Domains (1) summary
      pfam02827
      Location:270
      PKI; cAMP-dependent protein kinase inhibitor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      163500131..163568078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498926.4XP_006498989.1  cAMP-dependent protein kinase inhibitor gamma isoform X1

      See identical proteins and their annotated locations for XP_006498989.1

      UniProtKB/Swiss-Prot
      O70139
      UniProtKB/TrEMBL
      Q3TP50
      Conserved Domains (1) summary
      pfam02827
      Location:270
      PKI; cAMP-dependent protein kinase inhibitor
    2. XM_030248482.1XP_030104342.1  cAMP-dependent protein kinase inhibitor gamma isoform X1

      Conserved Domains (1) summary
      pfam02827
      Location:270
      PKI; cAMP-dependent protein kinase inhibitor
    3. XM_030248487.1XP_030104347.1  cAMP-dependent protein kinase inhibitor gamma isoform X1

      Conserved Domains (1) summary
      pfam02827
      Location:270
      PKI; cAMP-dependent protein kinase inhibitor

    RNA

    1. XR_003951364.1 RNA Sequence

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