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    Pigf phosphatidylinositol glycan anchor biosynthesis, class F [ Mus musculus (house mouse) ]

    Gene ID: 18701, updated on 22-Sep-2022

    Summary

    Official Symbol
    Pigfprovided by MGI
    Official Full Name
    phosphatidylinositol glycan anchor biosynthesis, class Fprovided by MGI
    Primary source
    MGI:MGI:99462
    See related
    Ensembl:ENSMUSG00000024145 AllianceGenome:MGI:99462
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable mannose-ethanolamine phosphotransferase activity. Involved in GPI anchor biosynthetic process. Located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. Orthologous to human PIGF (phosphatidylinositol glycan anchor biosynthesis class F). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 37.0), bladder adult (RPKM 17.1) and 20 other tissues See more
    Orthologs
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    Genomic context

    See Pigf in Genome Data Viewer
    Location:
    17 E4; 17 56.9 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (87304684..87332975, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (86997259..87025401, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (87396599..87424741, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene hapless 2-like Neighboring gene predicted gene, 50012 Neighboring gene ras homolog family member Q Neighboring gene cysteine-rich PDZ-binding protein Neighboring gene predicted gene, 30421 Neighboring gene predicted gene, 24648

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in GPI anchor biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in GPI anchor biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    phosphatidylinositol-glycan biosynthesis class F protein
    Names
    PIG-F
    phosphatidylinositol glycan, class F
    NP_032864.1
    XP_036016296.1
    XP_036016297.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001411401.1NP_001398330.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    2. NM_001411402.1NP_001398331.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    3. NM_001411403.1NP_001398332.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    4. NM_001411404.1NP_001398333.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    5. NM_001411405.1NP_001398334.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    6. NM_001411406.1NP_001398335.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    7. NM_001411407.1NP_001398336.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    8. NM_001411408.1NP_001398337.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    9. NM_001411409.1NP_001398338.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    10. NM_001411410.1NP_001398339.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    11. NM_001411411.1NP_001398340.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    12. NM_001411412.1NP_001398341.1  phosphatidylinositol-glycan biosynthesis class F protein

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    13. NM_008838.2NP_032864.1  phosphatidylinositol-glycan biosynthesis class F protein

      See identical proteins and their annotated locations for NP_032864.1

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
      Consensus CDS
      CCDS29011.1
      UniProtKB/Swiss-Prot
      O09101
      UniProtKB/TrEMBL
      A0A8C6GVZ1
      Related
      ENSMUSP00000024957.7, ENSMUST00000024957.7
      Conserved Domains (1) summary
      pfam06699
      Location:22204
      PIG-F; GPI biosynthesis protein family Pig-F

    RNA

    1. NR_177246.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    2. NR_177247.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492
    3. NR_177248.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC127695, AC154492

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      87304684..87332975 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160404.1XP_036016297.1  phosphatidylinositol-glycan biosynthesis class F protein isoform X1

      UniProtKB/Swiss-Prot
      O09101
      UniProtKB/TrEMBL
      A0A8C6GVZ1
      Conserved Domains (1) summary
      pfam06699
      Location:22204
      PIG-F; GPI biosynthesis protein family Pig-F
    2. XM_036160403.1XP_036016296.1  phosphatidylinositol-glycan biosynthesis class F protein isoform X1

      UniProtKB/Swiss-Prot
      O09101
      UniProtKB/TrEMBL
      A0A8C6GVZ1
      Conserved Domains (1) summary
      pfam06699
      Location:22204
      PIG-F; GPI biosynthesis protein family Pig-F