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    Piga phosphatidylinositol glycan anchor biosynthesis, class A [ Mus musculus (house mouse) ]

    Gene ID: 18700, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pigaprovided by MGI
    Official Full Name
    phosphatidylinositol glycan anchor biosynthesis, class Aprovided by MGI
    Primary source
    MGI:MGI:99461
    See related
    Ensembl:ENSMUSG00000031381
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pi; Pig-a; AI194334
    Expression
    Ubiquitous expression in liver E14.5 (RPKM 4.8), liver E14 (RPKM 4.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Piga in Genome Data Viewer
    Location:
    X F5; X 76.49 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (163202776..163216912)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (164419780..164433916)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (160857719..160871847)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene pirin Neighboring gene predicted gene, 22023 Neighboring gene vascular endothelial growth factor D Neighboring gene ankyrin repeat and SOCS box-containing 11 Neighboring gene chromobox protein homolog 1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol N-acetylglucosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    phosphatidylinositol N-acetylglucosaminyltransferase subunit A; N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein
    Names
    glcNAc-PI synthesis protein
    phosphatidylinositol glycan, class A
    phosphatidylinositol-glycan biosynthesis class A protein
    phosphatidylinositolglycan class A
    NP_035211.2
    XP_011246095.1
    XP_017173917.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011081.3NP_035211.2  phosphatidylinositol N-acetylglucosaminyltransferase subunit A

      See identical proteins and their annotated locations for NP_035211.2

      Status: VALIDATED

      Source sequence(s)
      AK032283, AL732475
      Consensus CDS
      CCDS30522.1
      UniProtKB/Swiss-Prot
      Q64323
      UniProtKB/TrEMBL
      A2AIH5
      Related
      ENSMUSP00000033754.8, ENSMUST00000033754.15
      Conserved Domains (1) summary
      cd03796
      Location:34433
      GT4_PIG-A-like; phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins

    RNA

    1. NR_152315.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL732475
      Related
      ENSMUST00000112257.10

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      163202776..163216912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017318428.3XP_017173917.1  N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein isoform X1

      UniProtKB/Swiss-Prot
      Q64323
      UniProtKB/TrEMBL
      A2AIH5
      Related
      ENSMUSP00000107874.2, ENSMUST00000112255.8
      Conserved Domains (1) summary
      cd03796
      Location:34433
      GT4_PIG-A-like; phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins
    2. XM_011247793.3XP_011246095.1  N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein isoform X2

      Related
      ENSMUSP00000146731.2, ENSMUST00000208697.2
      Conserved Domains (1) summary
      cl10013
      Location:13208
      Glycosyltransferase_GTB-type; glycosyltransferase family 1 and related proteins with GTB topology
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