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    Pex11a peroxisomal biogenesis factor 11 alpha [ Mus musculus (house mouse) ]

    Gene ID: 18631, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pex11aprovided by MGI
    Official Full Name
    peroxisomal biogenesis factor 11 alphaprovided by MGI
    Primary source
    MGI:MGI:1338788
    See related
    Ensembl:ENSMUSG00000030545
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PEX11; PEX11alpha
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 11.5), liver adult (RPKM 10.0) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Pex11a in Genome Data Viewer
    Location:
    7; 7 D2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (79385705..79392879, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (79735957..79743131, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (86882150..86887911, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene kinesin family member 7 Neighboring gene uncharacterized LOC118567517 Neighboring gene perilipin 1 Neighboring gene WD repeat domain 93 Neighboring gene predicted gene 44705

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within brown fat cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in peroxisome fission IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in peroxisome fission ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peroxisome membrane biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peroxisome organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of peroxisome size IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of peroxisome size ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of peroxisomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in peroxisomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    peroxisomal membrane protein 11A
    Names
    PEX11-alpha
    peroxin-11A
    peroxisomal biogenesis factor 11a
    protein PEX11 homolog alpha

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011068.2NP_035198.1  peroxisomal membrane protein 11A

      See identical proteins and their annotated locations for NP_035198.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the protein-coding transcript.
      Source sequence(s)
      AK076776, AK149387
      Consensus CDS
      CCDS21386.1
      UniProtKB/Swiss-Prot
      Q9Z211
      Related
      ENSMUSP00000032761.8, ENSMUST00000032761.8
      Conserved Domains (1) summary
      pfam05648
      Location:1237
      PEX11; Peroxisomal biogenesis factor 11 (PEX11)

    RNA

    1. NR_153403.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate internal exon compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AK076776, AK078954

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      79385705..79392879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152777.1XP_036008670.1  peroxisomal membrane protein 11A isoform X1

      Conserved Domains (1) summary
      pfam05648
      Location:1212
      PEX11; Peroxisomal biogenesis factor 11 (PEX11)
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