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    Oat ornithine aminotransferase [ Mus musculus (house mouse) ]

    Gene ID: 18242, updated on 8-Jul-2021

    Summary

    Official Symbol
    Oatprovided by MGI
    Official Full Name
    ornithine aminotransferaseprovided by MGI
    Primary source
    MGI:MGI:97394
    See related
    Ensembl:ENSMUSG00000030934
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    rh; rhg; AI194874
    Expression
    Broad expression in liver adult (RPKM 563.9), large intestine adult (RPKM 200.8) and 16 other tissues See more
    Orthologs
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    Genomic context

    See Oat in Genome Data Viewer
    Location:
    7 F3; 7 76.3 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (132159204..132178127, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (132557475..132576398, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (139749158..139768081, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene high mobility group box 1 pseudogene Neighboring gene predicted gene, 35249 Neighboring gene NK1 homeobox 2 Neighboring gene predicted gene, 46021

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    • Homologs of the Oat gene: The Oat gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
    • Orthologs from Annotation Pipeline: 398 organisms have orthologs with human gene Oat
    • Orthologs

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ornithine(lysine) transaminase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ornithine-oxo-acid transaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables pyridoxal phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in arginine catabolic process to glutamate IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in arginine catabolic process to proline via ornithine IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ornithine aminotransferase, mitochondrial
    Names
    ornithine--oxo-acid aminotransferase
    NP_058674.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016978.2NP_058674.1  ornithine aminotransferase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_058674.1

      Status: VALIDATED

      Source sequence(s)
      AK145877, AK168851, BY435126
      Consensus CDS
      CCDS21923.1
      UniProtKB/Swiss-Prot
      P29758
      UniProtKB/TrEMBL
      Q3TG75, Q3UKT3
      Related
      ENSMUSP00000081544.7, ENSMUST00000084500.8
      Conserved Domains (1) summary
      TIGR01885
      Location:40437
      Orn_aminotrans; ornithine aminotransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      132159204..132178127 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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