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    Nup50 nucleoporin 50 [ Mus musculus (house mouse) ]

    Gene ID: 18141, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nup50provided by MGI
    Official Full Name
    nucleoporin 50provided by MGI
    Primary source
    MGI:MGI:1351502
    See related
    Ensembl:ENSMUSG00000016619
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Np; Npap60; AI413123; 1700030K07Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 13.0), placenta adult (RPKM 9.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Nup50 in Genome Data Viewer
    Location:
    15 E2; 15 40.25 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (84800100..84827164)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (84923428..84942963)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (84753858..84773393)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46528 Neighboring gene RIKEN cDNA 4930513L16 gene Neighboring gene predicted gene 29666 Neighboring gene RIKEN cDNA 5031439G07 gene Neighboring gene microRNA 1249 Neighboring gene predicted gene, 39558

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within neural tube formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    nuclear pore complex protein Nup50
    Names
    50 kDa nucleoporin
    nuclear pore associated protein 60 kDa
    nucleoporin Nup50
    nucleoprotein 50

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016714.2NP_057923.2  nuclear pore complex protein Nup50

      See identical proteins and their annotated locations for NP_057923.2

      Status: PROVISIONAL

      Source sequence(s)
      BC059239
      Consensus CDS
      CCDS27714.1
      UniProtKB/Swiss-Prot
      Q9JIH2
      Related
      ENSMUSP00000131457.3, ENSMUST00000165443.4
      Conserved Domains (2) summary
      cd13170
      Location:348464
      RanBD_NUP50; Nucleoporin 50 Ran-binding domain
      pfam08911
      Location:364
      NUP50; NUP50 (Nucleoporin 50 kDa)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      84800100..84827164
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159225.1XP_036015118.1  nuclear pore complex protein Nup50 isoform X1

      Conserved Domains (2) summary
      cd13170
      Location:389505
      RanBD_NUP50; Nucleoporin 50 Ran-binding domain
      pfam08911
      Location:3105
      NUP50; NUP50 (Nucleoporin 50 kDa)
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