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    Emc8 ER membrane protein complex subunit 8 [ Mus musculus (house mouse) ]

    Gene ID: 18117, updated on 5-Feb-2019

    Summary

    Official Symbol
    Emc8provided by MGI
    Official Full Name
    ER membrane protein complex subunit 8provided by MGI
    Primary source
    MGI:MGI:1343095
    See related
    Ensembl:ENSMUSG00000031819
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Noc4; Cox4nb; Fam158b
    Expression
    Ubiquitous expression in ovary adult (RPKM 15.9), adrenal adult (RPKM 11.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Emc8 in Genome Data Viewer
    Location:
    8 E1; 8 69.98 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (120653914..120668112, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (123177814..123192012, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene 10614 Neighboring gene RIKEN cDNA 1190005I06 gene Neighboring gene predicted gene, 27021 Neighboring gene predicted gene, 33075 Neighboring gene cytochrome c oxidase subunit 4I1 Neighboring gene predicted gene, 39265

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Readthrough Gm27021

    Readthrough gene: Gm27021, Included gene: 1190005I06Rik

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    ER membrane protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ER membrane protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    ER membrane protein complex subunit 8
    Names
    COX4 neighbor
    neighbor of Cox4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010926.6NP_035056.1  ER membrane protein complex subunit 8

      See identical proteins and their annotated locations for NP_035056.1

      Status: VALIDATED

      Source sequence(s)
      AC103360
      Consensus CDS
      CCDS22719.1
      UniProtKB/Swiss-Prot
      O70378
      UniProtKB/TrEMBL
      Q3TPU5
      Related
      ENSMUSP00000034277.6, ENSMUST00000034277.13
      Conserved Domains (1) summary
      cd08060
      Location:6196
      MPN_UPF0172; Mov34/MPN/PAD-1 family: UPF0172 family of unknown function includes neighbor of COX4 (Noc4p)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      120653914..120668112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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