U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Rrp1 ribosomal RNA processing 1 [ Mus musculus (house mouse) ]

    Gene ID: 18114, updated on 18-Sep-2024

    Summary

    Official Symbol
    Rrp1provided by MGI
    Official Full Name
    ribosomal RNA processing 1provided by MGI
    Primary source
    MGI:MGI:1203500
    See related
    Ensembl:ENSMUSG00000061032 AllianceGenome:MGI:1203500
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nnp1; NNP-1
    Summary
    Predicted to be involved in rRNA processing. Predicted to be located in chromosome and nucleolus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human RRP1 (ribosomal RNA processing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 117.2), frontal lobe adult (RPKM 80.6) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rrp1 in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78236196..78248877, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78400362..78413043, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40709 Neighboring gene STARR-positive B cell enhancer ABC_E10623 Neighboring gene LSM7 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:77862123-77862306 Neighboring gene microRNA 6907 Neighboring gene cystatin B Neighboring gene microRNA 6410

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of preribosome, small subunit precursor IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ribosomal RNA processing protein 1 homolog A
    Names
    RRP1-like protein
    novel nuclear protein 1
    nucleolar protein Nop52
    protein NNP-1
    ribosomal RNA processing 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010925.3NP_035055.2  ribosomal RNA processing protein 1 homolog A

      See identical proteins and their annotated locations for NP_035055.2

      Status: VALIDATED

      Source sequence(s)
      AC160411
      Consensus CDS
      CCDS35961.1
      UniProtKB/Swiss-Prot
      O35712, P56183, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2
      Related
      ENSMUSP00000058785.10, ENSMUST00000062678.11
      Conserved Domains (1) summary
      pfam05997
      Location:11218
      Nop52; Nucleolar protein,Nop52

    RNA

    1. NR_190469.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC160411
    2. NR_190470.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC160411

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      78236196..78248877 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513338.4XP_006513401.1  ribosomal RNA processing protein 1 homolog A isoform X1

      See identical proteins and their annotated locations for XP_006513401.1

      UniProtKB/TrEMBL
      Q05CN2
      Conserved Domains (2) summary
      pfam05997
      Location:1156
      Nop52; Nucleolar protein,Nop52
      cl30717
      Location:299424
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]