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    Nktr natural killer tumor recognition sequence [ Mus musculus (house mouse) ]

    Gene ID: 18087, updated on 31-Jan-2019

    Summary

    Official Symbol
    Nktrprovided by MGI
    Official Full Name
    natural killer tumor recognition sequenceprovided by MGI
    Primary source
    MGI:MGI:97346
    See related
    Ensembl:ENSMUSG00000032525
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D9Wsu172e; 5330401F18Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 21.4), CNS E14 (RPKM 18.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nktr in Genome Data Viewer
    Location:
    9 F4; 9 72.57 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (121716535..121756842)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (121628299..121665959)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene SEC22 homolog C, vesicle trafficking protein Neighboring gene SS18, nBAF chromatin remodeling complex subunit like 2 Neighboring gene RIKEN cDNA E530011L22 gene Neighboring gene zinc finger protein 651 Neighboring gene kelch-like 40 Neighboring gene hedgehog acyltransferase-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cyclosporin A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cyclosporin A binding ISO
    Inferred from Sequence Orthology
    more info
     
    isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptidyl-prolyl cis-trans isomerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    protein peptidyl-prolyl isomerization ISO
    Inferred from Sequence Orthology
    more info
     
    protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    NK-tumor recognition protein
    Names
    NK-TR protein
    PPIase
    cyclophilin-related protein
    natural killer tumor recognition protein
    natural-killer cells cyclophilin-related protein
    peptidyl-prolyl cis-trans isomerase NKTR
    NP_035048.3
    XP_006512034.1
    XP_006512041.1
    XP_011241241.1
    XP_011241242.1
    XP_017168693.1
    XP_017168694.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010918.2NP_035048.3  NK-tumor recognition protein

      See identical proteins and their annotated locations for NP_035048.3

      Status: VALIDATED

      Source sequence(s)
      CAAA01064851, L04289
      Consensus CDS
      CCDS23636.1
      UniProtKB/Swiss-Prot
      P30415
      Related
      ENSMUSP00000035112.5, ENSMUST00000035112.12
      Conserved Domains (1) summary
      cl00197
      Location:7174
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      121716535..121756842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511971.3XP_006512034.1  NK-tumor recognition protein isoform X1

      Conserved Domains (1) summary
      cl00197
      Location:109276
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...
    2. XM_006511978.1XP_006512041.1  NK-tumor recognition protein isoform X5

      See identical proteins and their annotated locations for XP_006512041.1

      Conserved Domains (1) summary
      pfam00160
      Location:163
      Pro_isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
    3. XM_017313205.1XP_017168694.1  NK-tumor recognition protein isoform X4

    4. XM_011242939.2XP_011241241.1  NK-tumor recognition protein isoform X2

      Conserved Domains (1) summary
      cl00197
      Location:7174
      cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...
    5. XM_017313204.1XP_017168693.1  NK-tumor recognition protein isoform X3

    6. XM_011242940.2XP_011241242.1  NK-tumor recognition protein isoform X5

      See identical proteins and their annotated locations for XP_011241242.1

      Conserved Domains (1) summary
      pfam00160
      Location:163
      Pro_isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

    RNA

    1. XR_871176.2 RNA Sequence

    2. XR_871177.2 RNA Sequence

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