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    Nfs1 nitrogen fixation gene 1 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 18041, updated on 31-Jan-2019

    Summary

    Official Symbol
    Nfs1provided by MGI
    Official Full Name
    nitrogen fixation gene 1 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1316706
    See related
    Ensembl:ENSMUSG00000027618
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    m-Nfs1; m-Nfsl; AA987187
    Expression
    Ubiquitous expression in kidney adult (RPKM 43.8), adrenal adult (RPKM 39.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nfs1 in Genome Data Viewer
    Location:
    2; 2 H1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (156123637..156144186, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (155949373..155969922, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene sperm associated antigen 4 Neighboring gene copine I Neighboring gene RNA binding motif protein 12 Neighboring gene reactive oxygen species modulator 1 Neighboring gene RNA binding motif protein 39 Neighboring gene PHD finger protein 20

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    cysteine desulfurase activity ISO
    Inferred from Sequence Orthology
    more info
     
    iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    Mo-molybdopterin cofactor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    [2Fe-2S] cluster assembly IEA
    Inferred from Electronic Annotation
    more info
     
    iron incorporation into metallo-sulfur cluster IDA
    Inferred from Direct Assay
    more info
    PubMed 
    iron incorporation into metallo-sulfur cluster ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cysteine desulfurase, mitochondrial
    Names
    nifS-like (sic)
    nitrogen fixation gene, yeast homolog 1
    NP_035041.2
    XP_006498960.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010911.2NP_035041.2  cysteine desulfurase, mitochondrial

      See identical proteins and their annotated locations for NP_035041.2

      Status: VALIDATED

      Source sequence(s)
      AK004077, AK132838
      Consensus CDS
      CCDS16962.1
      UniProtKB/Swiss-Prot
      Q9Z1J3
      UniProtKB/TrEMBL
      Q9CTB2
      Related
      ENSMUSP00000029147.9, ENSMUST00000029147.15
      Conserved Domains (2) summary
      PRK14012
      Location:60459
      PRK14012; cysteine desulfurase; Provisional
      pfam00266
      Location:62423
      Aminotran_5; Aminotransferase class-V

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      156123637..156144186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498897.1XP_006498960.1  cysteine desulfurase, mitochondrial isoform X1

      Conserved Domains (2) summary
      pfam00266
      Location:62372
      Aminotran_5; Aminotransferase class-V
      cl18945
      Location:60408
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    RNA

    1. XR_001781173.1 RNA Sequence

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