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    eat-6 Sodium/potassium-transporting ATPase subunit alpha [ Caenorhabditis elegans ]

    Gene ID: 179796, updated on 9-Oct-2018

    Summary

    Gene symbol
    eat-6
    Gene description
    Sodium/potassium-transporting ATPase subunit alpha
    Primary source
    WormBase:WBGene00001137
    Locus tag
    CELE_B0365.3
    Gene type
    protein coding
    RNA name
    Sodium/potassium-transporting ATPase subunit alpha
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

    Genomic context

    See eat-6 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (13126646..13129987, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ATP-citrate synthase Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene hypothetical protein

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    sodium:potassium-exchanging ATPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sodium:potassium-exchanging ATPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    sodium:potassium-exchanging ATPase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sodium:potassium-exchanging ATPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    ATP hydrolysis coupled proton transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    action potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular potassium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular sodium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    establishment or maintenance of transmembrane electrochemical gradient IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    potassium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    potassium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    potassium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    regulation of membrane potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of muscle contraction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    reproduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sodium ion export across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    sodium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sodium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    Sodium/potassium-transporting ATPase subunit alpha
    NP_506269.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      13126646..13129987 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073868.3NP_506269.1  Sodium/potassium-transporting ATPase subunit alpha [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506269.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P90735
      Conserved Domains (6) summary
      smart00831
      Location:1892
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      COG4087
      Location:644725
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01106
      Location:6996
      ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
      pfam00122
      Location:112343
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:772981
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam13246
      Location:404494
      Cation_ATPase; Cation transport ATPase (P-type)
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