Format

Send to:

Choose Destination
    • Showing Current items.

    Myom2 myomesin 2 [ Mus musculus (house mouse) ]

    Gene ID: 17930, updated on 23-Jun-2021

    Summary

    Official Symbol
    Myom2provided by MGI
    Official Full Name
    myomesin 2provided by MGI
    Primary source
    MGI:MGI:1328358
    See related
    Ensembl:ENSMUSG00000031461
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW146149
    Expression
    Biased expression in heart adult (RPKM 109.4), mammary gland adult (RPKM 11.0) and 1 other tissue See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Myom2 in Genome Data Viewer
    Location:
    8; 8 A1.1
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (15107653..15183420)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (15057653..15133420)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (15057653..15133419)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35340 Neighboring gene expressed sequence BB014433 Neighboring gene predicted gene, 24231 Neighboring gene predicted gene, 35392

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC141540, MGC141541

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural constituent of cytoskeleton TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in muscle contraction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within muscle contraction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in sarcomere organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in M band IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in M band IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in M band ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    myomesin-2
    Names
    skeletal muscle 165kD protein
    skeletal muscle 165kDa protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008664.2NP_032690.2  myomesin-2

      See identical proteins and their annotated locations for NP_032690.2

      Status: VALIDATED

      Source sequence(s)
      AJ001038, AK142174, AV232298, BC115722
      Consensus CDS
      CCDS22123.1
      UniProtKB/TrEMBL
      O55124, Q14BI5, Q3UQS9
      Related
      ENSMUSP00000033842.4, ENSMUST00000033842.4
      Conserved Domains (6) summary
      cd05891
      Location:13441435
      IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
      smart00409
      Location:940995
      IG; Immunoglobulin
      cd00063
      Location:383475
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:295299
      Ig; Ig strand B [structural motif]
      cd20951
      Location:154247
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:290372
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      15107653..15183420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153791.1XP_036009684.1  myomesin-2 isoform X2

      Conserved Domains (6) summary
      cd05891
      Location:13441435
      IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
      smart00409
      Location:940995
      IG; Immunoglobulin
      cd00063
      Location:383475
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:295299
      Ig; Ig strand B [structural motif]
      cd20951
      Location:154247
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:290372
      Ig; Immunoglobulin domain
    2. XM_006508727.4XP_006508790.1  myomesin-2 isoform X1

      Conserved Domains (5) summary
      cd05891
      Location:13671458
      Ig_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein (also known as myomesin-2)
      smart00409
      Location:9631018
      IG; Immunoglobulin
      cd00063
      Location:406498
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:177269
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:313395
      Ig; Immunoglobulin domain
    3. XM_036153789.1XP_036009682.1  myomesin-2 isoform X2

      Conserved Domains (6) summary
      cd05891
      Location:13441435
      IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
      smart00409
      Location:940995
      IG; Immunoglobulin
      cd00063
      Location:383475
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:295299
      Ig; Ig strand B [structural motif]
      cd20951
      Location:154247
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:290372
      Ig; Immunoglobulin domain
    4. XM_036153790.1XP_036009683.1  myomesin-2 isoform X2

      Conserved Domains (6) summary
      cd05891
      Location:13441435
      IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
      smart00409
      Location:940995
      IG; Immunoglobulin
      cd00063
      Location:383475
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:295299
      Ig; Ig strand B [structural motif]
      cd20951
      Location:154247
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:290372
      Ig; Immunoglobulin domain
    5. XM_006508728.5XP_006508791.1  myomesin-2 isoform X2

      See identical proteins and their annotated locations for XP_006508791.1

      UniProtKB/TrEMBL
      Q14BI5
      Conserved Domains (6) summary
      cd05891
      Location:13441435
      IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
      smart00409
      Location:940995
      IG; Immunoglobulin
      cd00063
      Location:383475
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:295299
      Ig; Ig strand B [structural motif]
      cd20951
      Location:154247
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:290372
      Ig; Immunoglobulin domain
    6. XM_036153788.1XP_036009681.1  myomesin-2 isoform X2

      Conserved Domains (6) summary
      cd05891
      Location:13441435
      IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
      smart00409
      Location:940995
      IG; Immunoglobulin
      cd00063
      Location:383475
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:295299
      Ig; Ig strand B [structural motif]
      cd20951
      Location:154247
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:290372
      Ig; Immunoglobulin domain
    Support Center