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    Fam89b family with sequence similarity 89, member B [ Mus musculus (house mouse) ]

    Gene ID: 17826, updated on 31-Jan-2019

    Summary

    Official Symbol
    Fam89bprovided by MGI
    Official Full Name
    family with sequence similarity 89, member Bprovided by MGI
    Primary source
    MGI:MGI:106595
    See related
    Ensembl:ENSMUSG00000024939
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MMTV; Mtvr2; 1110021A21Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 186.5), ovary adult (RPKM 160.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Fam89b in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (5728087..5729666, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (5728087..5729666, complement)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene pecanex homolog 3 Neighboring gene mitogen-activated protein kinase kinase kinase 11 Neighboring gene potassium channel, subfamily K, member 7 Neighboring gene EH domain binding protein 1-like 1 Neighboring gene Sjogren syndrome/scleroderma autoantigen 1 Neighboring gene latent transforming growth factor beta binding protein 3 Neighboring gene SCY1-like 1 (S. cerevisiae)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Potential readthrough

    Included gene: Sssca1

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription corepressor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lamellipodium IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    leucine repeat adapter protein 25
    Names
    C184L ORF2 protein
    C184M protein
    MMTV receptor
    mammary tumor virus receptor 2
    protein FAM89B

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023166.2NP_075655.2  leucine repeat adapter protein 25 isoform 2

      See identical proteins and their annotated locations for NP_075655.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      BC056166, CJ132526
      Consensus CDS
      CCDS50361.1
      UniProtKB/TrEMBL
      Q7TMI7
      Related
      ENSMUSP00000124294.1, ENSMUST00000161368.1
    2. NM_181452.2NP_852117.2  leucine repeat adapter protein 25 isoform 1

      See identical proteins and their annotated locations for NP_852117.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BC056166, BM942073, CJ132526
      Consensus CDS
      CCDS37890.1
      UniProtKB/Swiss-Prot
      Q9QUI1
      UniProtKB/TrEMBL
      Q7TMI7
      Related
      ENSMUSP00000097538.3, ENSMUST00000099955.3
      Conserved Domains (1) summary
      pfam14854
      Location:74127
      LURAP; Leucine rich adaptor protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      5728087..5729666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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