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    Msl3 MSL complex subunit 3 [ Mus musculus (house mouse) ]

    Gene ID: 17692, updated on 2-Oct-2018

    Summary

    Official Symbol
    Msl3provided by MGI
    Official Full Name
    MSL complex subunit 3provided by MGI
    Primary source
    MGI:MGI:1341851
    See related
    Ensembl:ENSMUSG00000031358 Vega:OTTMUSG00000019558
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Msl31; Msl3l1; AU018931
    Expression
    Ubiquitous expression in bladder adult (RPKM 7.1), placenta adult (RPKM 6.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Msl3 in Genome Data Viewer
    Location:
    X; X F5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (168651267..168674335, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (165092049..165111834, complement)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene FERM and PDZ domain containing 4 Neighboring gene coiled-coil-helix-coiled-coil-helix domain-containing protein 5 pseudogene Neighboring gene predicted gene, 39550 Neighboring gene Rho GTPase activating protein 6 Neighboring gene amelogenin, X-linked Neighboring gene holocytochrome c synthetase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin silencing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone H2A acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone H4 acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone H4-K16 acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone H4-K16 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    histone acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone deacetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    MSL complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    MSL complex ISO
    Inferred from Sequence Orthology
    more info
     
    NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    male-specific lethal 3 homolog
    Names
    male-specific lethal-3 homolog 1
    male-specific lethal-3 protein-like 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010832.5NP_034962.2  male-specific lethal 3 homolog

      See identical proteins and their annotated locations for NP_034962.2

      Status: VALIDATED

      Source sequence(s)
      AL671489
      Consensus CDS
      CCDS41211.1
      UniProtKB/Swiss-Prot
      Q9WVG9
      Related
      ENSMUSP00000107765.1, OTTMUSP00000021100, ENSMUST00000112137.1, OTTMUST00000046702
      Conserved Domains (2) summary
      pfam05712
      Location:117451
      MRG; MRG
      pfam12258
      Location:254353
      Microcephalin; Microcephalin protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      168651267..168674335 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528741.3XP_006528804.1  male-specific lethal 3 homolog isoform X1

      See identical proteins and their annotated locations for XP_006528804.1

      UniProtKB/Swiss-Prot
      Q9WVG9
      Related
      ENSMUSP00000033725.9, OTTMUSP00000021099, ENSMUST00000033725.15, OTTMUST00000046701
      Conserved Domains (3) summary
      pfam05712
      Location:176510
      MRG; MRG
      pfam11717
      Location:1473
      Tudor-knot; RNA binding activity-knot of a chromodomain
      pfam12258
      Location:313412
      Microcephalin; Microcephalin protein
    2. XM_006528742.3XP_006528805.1  male-specific lethal 3 homolog isoform X2

      Conserved Domains (3) summary
      pfam05712
      Location:175509
      MRG; MRG
      pfam11717
      Location:1473
      Tudor-knot; RNA binding activity-knot of a chromodomain
      pfam12258
      Location:312411
      Microcephalin; Microcephalin protein
    3. XM_006528745.3XP_006528808.1  male-specific lethal 3 homolog isoform X5

      Conserved Domains (2) summary
      pfam05712
      Location:106446
      MRG; MRG
      pfam12258
      Location:253352
      Microcephalin; Microcephalin protein
    4. XM_006528744.3XP_006528807.1  male-specific lethal 3 homolog isoform X4

      Conserved Domains (3) summary
      smart00298
      Location:1456
      CHROMO; Chromatin organization modifier domain
      pfam05712
      Location:144484
      MRG; MRG
      pfam12258
      Location:291390
      Microcephalin; Microcephalin protein
    5. XM_017318415.1XP_017173904.1  male-specific lethal 3 homolog isoform X3

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