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    spl-1 Sphingosine-1-phosphate lyase [ Caenorhabditis elegans ]

    Gene ID: 176857, updated on 19-Aug-2018

    Summary

    Gene symbol
    spl-1
    Gene description
    Sphingosine-1-phosphate lyase
    Primary source
    WormBase:WBGene00004981
    Locus tag
    CELE_Y66H1B.4
    Gene type
    protein coding
    RNA name
    Sphingosine-1-phosphate lyase
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

    Genomic context

    See spl-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (380018..383179, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene CaDHerin family Neighboring gene ncRNA Neighboring gene FiLamiN (actin binding protein) homolog Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Ribosomal Protein, Small subunit

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    carboxy-lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    pyridoxal phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    sphinganine-1-phosphate aldolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sphinganine-1-phosphate aldolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    ameboidal-type cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    carboxylic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    sphingolipid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sphingolipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sphingolipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Sphingosine-1-phosphate lyase
    NP_499913.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      380018..383179 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067512.5NP_499913.1  Sphingosine-1-phosphate lyase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499913.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9Y194
      Conserved Domains (1) summary
      cd06450
      Location:138501
      DOPA_deC_like; DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and ...
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