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    aakg-5 AMP-Activated protein Kinase Gamma subunit [ Caenorhabditis elegans ]

    Gene ID: 174556, updated on 8-Dec-2022

    Summary

    Gene symbol
    aakg-5
    Gene description
    AMP-Activated protein Kinase Gamma subunit
    Primary source
    WormBase:WBGene00011276
    Locus tag
    CELE_R53.7
    See related
    AllianceGenome:WB:WBGene00011276
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be involved in cellular response to glucose starvation; protein phosphorylation; and regulation of catalytic activity. Predicted to be part of nucleotide-activated protein kinase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including epithelial cell; excretory cell; hermaphrodite gonad; neurons; and rectal epithelium. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See aakg-5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (9971050..9974704, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative DNA replication complex GINS protein PSF1 Neighboring gene Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    AMP-Activated protein Kinase Gamma subunit
    NP_496155.1
    • Product from WormBase gene class aakg;
      Confirmed by transcript evidence
    NP_871971.1
    • Product from WormBase gene class aakg;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9971050..9974704 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_182171.4NP_871971.1  AMP-Activated protein Kinase Gamma subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_871971.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I112
      Conserved Domains (4) summary
      COG0517
      Location:257374
      CBS; CBS domain [Signal transduction mechanisms]
      cd02205
      Location:330448
      CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
      cd04618
      Location:184300
      CBS_pair_5; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
      cd04621
      Location:256377
      CBS_pair_8; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
    2. NM_063754.6NP_496155.1  AMP-Activated protein Kinase Gamma subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496155.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22022
      Conserved Domains (4) summary
      COG0517
      Location:229346
      CBS; CBS domain [Signal transduction mechanisms]
      cd02205
      Location:302420
      CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
      cd04618
      Location:156272
      CBS_pair_5; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
      cd04621
      Location:228349
      CBS_pair_8; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...