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    Clec10a C-type lectin domain family 10, member A [ Mus musculus (house mouse) ]

    Gene ID: 17312, updated on 27-Jan-2018

    Summary

    Official Symbol
    Clec10aprovided by MGI
    Official Full Name
    C-type lectin domain family 10, member Aprovided by MGI
    Primary source
    MGI:MGI:96975
    See related
    Ensembl:ENSMUSG00000000318 Vega:OTTMUSG00000006033
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mgl; Mgl1; CD301a; M-ASGP-BP-1
    Expression
    Biased expression in mammary gland adult (RPKM 20.4), bladder adult (RPKM 15.0) and 9 other tissues See more

    Genomic context

    See Clec10a in Genome Data Viewer
    Location:
    11 B3; 11 42.99 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (70166623..70170836)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69980276..69984336)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene asialoglycoprotein receptor 2 Neighboring gene macrophage galactose N-acetyl-galactosamine specific lectin 2 Neighboring gene solute carrier family 16 (monocarboxylic acid transporters), member 11 Neighboring gene solute carrier family 16 (monocarboxylic acid transporters), member 13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    C-type lectin domain family 10 member A
    Names
    macrophage asialoglycoprotein-binding protein 1
    macrophage galactose N-acetyl-galactosamine specific lectin 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204252.1NP_001191181.1  C-type lectin domain family 10 member A isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AL669869
      Consensus CDS
      CCDS56784.1
      UniProtKB/TrEMBL
      F8WHB7
      Related
      ENSMUSP00000000327.6, OTTMUSP00000062283, ENSMUST00000000327.12, OTTMUST00000111307
      Conserved Domains (2) summary
      cd03590
      Location:174299
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)
      pfam03954
      Location:14164
      Lectin_N; Hepatic lectin, N-terminal domain
    2. NM_010796.3NP_034926.1  C-type lectin domain family 10 member A isoform 2

      See identical proteins and their annotated locations for NP_034926.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AL669869
      Consensus CDS
      CCDS24936.1
      UniProtKB/Swiss-Prot
      P49300
      Related
      ENSMUSP00000099631.3, OTTMUSP00000006284, ENSMUST00000102571.9, OTTMUST00000013562
      Conserved Domains (2) summary
      cd03590
      Location:173298
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)
      pfam03954
      Location:16163
      Lectin_N; Hepatic lectin, N-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      70166623..70170836
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_187026.1 Reference GRCm38.p4 NOD/MrkTac

      Range
      271090..275303
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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