Format

Send to:

Choose Destination
    • Showing Current items.

    Max Max protein [ Mus musculus (house mouse) ]

    Gene ID: 17187, updated on 25-Nov-2021

    Summary

    Official Symbol
    Maxprovided by MGI
    Official Full Name
    Max proteinprovided by MGI
    Primary source
    MGI:MGI:96921
    See related
    Ensembl:ENSMUSG00000059436
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; AA960152; AI875693
    Expression
    Ubiquitous expression in large intestine adult (RPKM 24.2), small intestine adult (RPKM 21.0) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Max in Genome Data Viewer
    Location:
    12 C3; 12 33.78 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (76984043..77009123, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (76937269..76962323, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (78038256..78063235, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene farnesyltransferase, CAAX box, beta Neighboring gene predicted gene, 46357 Neighboring gene predicted gene, 46358 Neighboring gene predicted gene, 35041 Neighboring gene predicted gene, 35189

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    enables E-box binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of MLL1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Mad-Max complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Myc-Max complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of Myc-Max complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in PML body ISO
    Inferred from Sequence Orthology
    more info
     
    part_of RNA polymerase II transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of RNA polymerase II transcription regulator complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-DNA complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein max
    Names
    myc-associated factor X
    myc-binding novel HLH/LZ protein
    protein myn

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001146176.1NP_001139648.1  protein max isoform 2

      See identical proteins and their annotated locations for NP_001139648.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon in the 5' coding region compared to variant 1 but maintains the reading frame. The encoded protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AC124556, AK080431, BB841019
      Consensus CDS
      CCDS49094.1
      UniProtKB/TrEMBL
      Q8C4Y1
      Related
      ENSMUSP00000080778.6, ENSMUST00000082136.7
      Conserved Domains (1) summary
      cd11406
      Location:1583
      bHLHzip_Max; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in protein Max and similar proteins
    2. NM_001361663.1NP_001348592.1  protein max isoform 3

      Status: VALIDATED

      Source sequence(s)
      BB841019, BC138671, BE947905
      Conserved Domains (1) summary
      cd11406
      Location:2492
      bHLHzip_Max; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in protein Max and similar proteins
    3. NM_001361664.1NP_001348593.1  protein max isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC124556, AK080431, BB841019, BC138671, BE947905
    4. NM_008558.2NP_032584.2  protein max isoform 1

      See identical proteins and their annotated locations for NP_032584.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC124556, BB841019, BC138671
      Consensus CDS
      CCDS36479.1
      UniProtKB/TrEMBL
      B2RS19
      Related
      ENSMUSP00000106025.4, ENSMUST00000110395.11
      Conserved Domains (1) summary
      cd11406
      Location:2492
      bHLHzip_Max; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in protein Max and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      76984043..77009123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157209.1XP_036013102.1  protein max isoform X2

    2. XM_030246570.2XP_030102430.1  protein max isoform X2

    3. XM_006515523.5XP_006515586.1  protein max isoform X1

      See identical proteins and their annotated locations for XP_006515586.1

      UniProtKB/TrEMBL
      A0A1W2P7P4
      Related
      ENSMUSP00000151710.2, ENSMUST00000218640.2
      Conserved Domains (1) summary
      cl00081
      Location:2256
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
    4. XM_030246571.1XP_030102431.1  protein max isoform X2

    5. XM_017314968.3XP_017170457.1  protein max isoform X2

    RNA

    1. XR_872708.4 RNA Sequence

    2. XR_003949992.2 RNA Sequence

    Support Center