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    Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) [ Mus musculus (house mouse) ]

    Gene ID: 17134, updated on 31-Jan-2019

    Summary

    Official Symbol
    Mafgprovided by MGI
    Official Full Name
    v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)provided by MGI
    Primary source
    MGI:MGI:96911
    See related
    Ensembl:ENSMUSG00000051510
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA545192; C630022N07Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 18.1), adrenal adult (RPKM 17.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Mafg in Genome Data Viewer
    Location:
    11 E2; 11 84.35 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (120625117..120633547, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (120489662..120494861, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene phosphate cytidylyltransferase 2, ethanolamine Neighboring gene sirtuin 7 Neighboring gene microRNA 6936 Neighboring gene pyrroline-5-carboxylate reductase 1 Neighboring gene myeloid-associated differentiation marker-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    DNA-binding transcription activator activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase II proximal promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase II proximal promoter sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity TAS
    Traceable Author Statement
    more info
    PubMed 
    sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    adult behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    in utero embryonic development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cellular pH ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of epidermal cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of epidermal cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    transcription factor MafG
    Names
    V-maf musculoaponeurotic fibrosarcoma oncogene homolog G
    avian musculoaponeurotic fibrosarcoma virus (v-maf) AS42 oncogene, protein G

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010756.3NP_034886.1  transcription factor MafG

      See identical proteins and their annotated locations for NP_034886.1

      Status: VALIDATED

      Source sequence(s)
      BC052633
      Consensus CDS
      CCDS25748.1
      UniProtKB/Swiss-Prot
      O54790
      Related
      ENSMUSP00000053899.7, ENSMUST00000058162.13
      Conserved Domains (1) summary
      cd14717
      Location:46115
      bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      120625117..120633547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314307.1XP_017169796.1  transcription factor MafG isoform X1

    2. XM_017314311.1XP_017169800.1  transcription factor MafG isoform X2

      UniProtKB/Swiss-Prot
      O54790
      Conserved Domains (1) summary
      cd14717
      Location:46115
      bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
    3. XM_017314308.1XP_017169797.1  transcription factor MafG isoform X2

      UniProtKB/Swiss-Prot
      O54790
      Related
      ENSMUSP00000101788.1, ENSMUST00000106182.7
      Conserved Domains (1) summary
      cd14717
      Location:46115
      bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
    4. XM_017314309.1XP_017169798.1  transcription factor MafG isoform X2

      UniProtKB/Swiss-Prot
      O54790
      Related
      ENSMUSP00000101787.1, ENSMUST00000106181.7
      Conserved Domains (1) summary
      cd14717
      Location:46115
      bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
    5. XM_017314310.1XP_017169799.1  transcription factor MafG isoform X2

      UniProtKB/Swiss-Prot
      O54790
      Related
      ENSMUSP00000101786.1, ENSMUST00000106180.1
      Conserved Domains (1) summary
      cd14717
      Location:46115
      bZIP_Maf_small; Basic leucine zipper (bZIP) domain of small musculoaponeurotic fibrosarcoma (Maf) proteins: a DNA-binding and dimerization domain
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