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    Mxd1 MAX dimerization protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 17119, updated on 2-Oct-2018

    Summary

    Official Symbol
    Mxd1provided by MGI
    Official Full Name
    MAX dimerization protein 1provided by MGI
    Primary source
    MGI:MGI:96908
    See related
    Ensembl:ENSMUSG00000001156 Vega:OTTMUSG00000056544
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mad; Mad1; AW122478
    Expression
    Broad expression in small intestine adult (RPKM 105.0), colon adult (RPKM 95.6) and 15 other tissues See more
    Orthologs

    Genomic context

    See Mxd1 in Genome Data Viewer
    Location:
    6 D1; 6 37.75 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (86647044..86669326, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (86597038..86619153, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 46963 Neighboring gene aspartic peptidase, retroviral-like 1 Neighboring gene predicted gene, 38850 Neighboring gene small nuclear ribonucleoprotein 27 (U4/U6.U5) Neighboring gene germ cell-less, spermatogenesis associated 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II proximal promoter sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    max dimerization protein 1
    Names
    max dimerizer 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010751.3NP_034881.2  max dimerization protein 1

      See identical proteins and their annotated locations for NP_034881.2

      Status: VALIDATED

      Source sequence(s)
      AK031169, AK137548, AK151014, BY106585, CF925462
      Consensus CDS
      CCDS51835.1
      UniProtKB/TrEMBL
      Q8K1Z8
      Related
      ENSMUSP00000001184.7, OTTMUSP00000073258, ENSMUST00000001184.9, OTTMUST00000139669
      Conserved Domains (1) summary
      cd00083
      Location:53109
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      86647044..86669326 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505670.3XP_006505733.1  max dimerization protein 1 isoform X1

      Conserved Domains (1) summary
      cd00083
      Location:53109
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
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