Format

Send to:

Choose Destination
    • Showing Current items.

    Glmn glomulin, FKBP associated protein [ Mus musculus (house mouse) ]

    Gene ID: 170823, updated on 23-Jun-2021

    Summary

    Official Symbol
    Glmnprovided by MGI
    Official Full Name
    glomulin, FKBP associated proteinprovided by MGI
    Primary source
    MGI:MGI:2141180
    See related
    Ensembl:ENSMUSG00000029276
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fap48; Fap68; AW227515; 9330160J16Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 4.4), CNS E18 (RPKM 3.9) and 20 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Glmn in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (107696828..107745754, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (107548962..107597888, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (107977986..108026907, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene BTB (POZ) domain containing 8 Neighboring gene predicted gene, 33885 Neighboring gene LSM12 homolog pseudogene Neighboring gene RIKEN cDNA 1700028K03 gene Neighboring gene RNA polymerase II associated protein 2 Neighboring gene RIKEN cDNA A930041C12 gene Neighboring gene Gfi1 +35 kb enhancer

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6885

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables hepatocyte growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin-protein transferase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ubiquitin-protein transferase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Cul3-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Cul4A-RING E3 ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cullin-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    glomulin
    Names
    FAP
    FK506-binding protein-associated protein
    FKBP-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001161738.1NP_001155210.1  glomulin isoform a

      See identical proteins and their annotated locations for NP_001155210.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
      Source sequence(s)
      AC134411, AK034160
      Consensus CDS
      CCDS19505.1
      UniProtKB/Swiss-Prot
      Q8BZM1
      Related
      ENSMUSP00000080766.3, ENSMUST00000082121.9
      Conserved Domains (1) summary
      pfam08568
      Location:1527
      Kinetochor_Ybp2; Uncharacterized protein family, YAP/Alf4/glomulin
    2. NM_001161739.1NP_001155211.1  glomulin isoform b

      See identical proteins and their annotated locations for NP_001155211.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two in-frame exons in the 3' coding region compared to variant 1. This results in a shorter protein (isoform b) compared to isoform a.
      Source sequence(s)
      AC117574, AC134411, AK169045
      Consensus CDS
      CCDS51587.1
      UniProtKB/Swiss-Prot
      Q8BZM1
      UniProtKB/TrEMBL
      Q3T9A5
      Related
      ENSMUSP00000098509.4, ENSMUST00000100949.10
      Conserved Domains (1) summary
      pfam08568
      Location:1462
      Kinetochor_Ybp2; uncharacterized protein family, YAP/Alf4/glomulin
    3. NM_133248.2NP_573511.2  glomulin isoform a

      See identical proteins and their annotated locations for NP_573511.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same isoform (a).
      Source sequence(s)
      AC134411, AK169045, BY013339
      Consensus CDS
      CCDS19505.1
      UniProtKB/Swiss-Prot
      Q8BZM1
      Related
      ENSMUSP00000077168.7, ENSMUST00000078021.13
      Conserved Domains (1) summary
      pfam08568
      Location:1527
      Kinetochor_Ybp2; Uncharacterized protein family, YAP/Alf4/glomulin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      107696828..107745754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249410.3XP_011247712.1  glomulin isoform X2

      Conserved Domains (1) summary
      pfam08568
      Location:14224
      Kinetochor_Ybp2; Uncharacterized protein family, YAP/Alf4/glomulin
    2. XM_030254179.1XP_030110039.1  glomulin isoform X2

      Conserved Domains (1) summary
      pfam08568
      Location:14224
      Kinetochor_Ybp2; Uncharacterized protein family, YAP/Alf4/glomulin
    3. XM_006534800.5XP_006534863.1  glomulin isoform X1

      See identical proteins and their annotated locations for XP_006534863.1

      UniProtKB/Swiss-Prot
      Q8BZM1
      Conserved Domains (1) summary
      pfam08568
      Location:1527
      Kinetochor_Ybp2; Uncharacterized protein family, YAP/Alf4/glomulin
    4. XM_017320694.3XP_017176183.1  glomulin isoform X2

      Conserved Domains (1) summary
      pfam08568
      Location:14224
      Kinetochor_Ybp2; Uncharacterized protein family, YAP/Alf4/glomulin

    RNA

    1. XR_001784631.2 RNA Sequence

      Related
      ENSMUST00000124546.8
    Support Center