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    Atp13a1 ATPase type 13A1 [ Mus musculus (house mouse) ]

    Gene ID: 170759, updated on 23-Jun-2021

    Summary

    Official Symbol
    Atp13a1provided by MGI
    Official Full Name
    ATPase type 13A1provided by MGI
    Primary source
    MGI:MGI:2180801
    See related
    Ensembl:ENSMUSG00000031862
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ca; Atp; catp; Cgi15; Atp13a; Cgi152
    Expression
    Ubiquitous expression in thymus adult (RPKM 77.4), ovary adult (RPKM 67.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Atp13a1 in Genome Data Viewer
    Location:
    8; 8 B3.3
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (70243813..70260399)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (69791163..69807749)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (72315062..72331648)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 19893 Neighboring gene zinc finger protein 866 Neighboring gene Gem-interacting protein Neighboring gene predicted gene, 33695 Neighboring gene lysophosphatidic acid receptor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane protein dislocase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cation transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in extraction of mislocalized protein from ER membrane ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    endoplasmic reticulum transmembrane helix translocase; manganese-transporting ATPase 13A1
    Names
    cation-transporting ATPase 2
    endoplasmic reticulum P5A-ATPase
    probable cation-transporting ATPase 13A1
    NP_573487.2
    XP_006509627.1
    XP_030099178.1
    XP_030099179.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133224.2NP_573487.2  endoplasmic reticulum transmembrane helix translocase

      See identical proteins and their annotated locations for NP_573487.2

      Status: VALIDATED

      Source sequence(s)
      AC157564, AK052057
      Consensus CDS
      CCDS22349.1
      UniProtKB/Swiss-Prot
      Q9EPE9
      Related
      ENSMUSP00000034326.7, ENSMUST00000034326.7
      Conserved Domains (5) summary
      COG4087
      Location:828881
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:821169
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:295507
      E1-E2_ATPase; E1-E2 ATPase
      pfam12710
      Location:640762
      HAD; haloacid dehalogenase-like hydrolase
      pfam13246
      Location:581664
      Cation_ATPase; Cation transport ATPase (P-type)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      70243813..70260399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509564.4XP_006509627.1  manganese-transporting ATPase 13A1 isoform X1

      Conserved Domains (1) summary
      cd07543
      Location:2111130
      P-type_ATPase_cation; P-type cation-transporting ATPases, similar to human cation-transporting ATPase type 13A1 (ATP13A1) and Saccharomyces manganese-transporting ATPase 1 Spf1p
    2. XM_030243318.1XP_030099178.1  manganese-transporting ATPase 13A1 isoform X2

      Conserved Domains (1) summary
      cl21460
      Location:29696
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    3. XM_030243319.1XP_030099179.1  manganese-transporting ATPase 13A1 isoform X3

      Conserved Domains (1) summary
      cl21460
      Location:1621
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    RNA

    1. XR_003947239.1 RNA Sequence

      Related
      ENSMUST00000238453.2
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