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    Snx18 sorting nexin 18 [ Mus musculus (house mouse) ]

    Gene ID: 170625, updated on 23-Jun-2021

    Summary

    Official Symbol
    Snx18provided by MGI
    Official Full Name
    sorting nexin 18provided by MGI
    Primary source
    MGI:MGI:2137642
    See related
    Ensembl:ENSMUSG00000042364
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sn; Snag1
    Expression
    Ubiquitous expression in ovary adult (RPKM 28.8), bladder adult (RPKM 12.6) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Snx18 in Genome Data Viewer
    Location:
    13; 13 D2.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (113728715..113755100, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (113592179..113618564, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (114382387..114408772, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4921509O07 gene Neighboring gene predicted gene, 31191 Neighboring gene predicted gene, 34471 Neighboring gene predicted gene, 53817 Neighboring gene predicted gene, 34528 Neighboring gene predicted gene, 34586 Neighboring gene heat shock protein 3 Neighboring gene predicted gene, 53818

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cleavage furrow formation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endosomal transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    colocalizes_with clathrin-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extrinsic component of cytoplasmic side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sorting nexin-18
    Names
    sorting nexin associated golgi protein 1
    sorting nexin-associated Golgi protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130796.4NP_570614.2  sorting nexin-18

      See identical proteins and their annotated locations for NP_570614.2

      Status: VALIDATED

      Source sequence(s)
      BC063089, BC137801, BP763454
      Consensus CDS
      CCDS36784.1
      UniProtKB/TrEMBL
      Q8C788
      Related
      ENSMUSP00000104864.4, ENSMUST00000109241.5
      Conserved Domains (3) summary
      cd07286
      Location:267394
      PX_SNX18; The phosphoinositide binding Phox Homology domain of Sorting Nexin 18
      cd07670
      Location:406612
      BAR_SNX18; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 18
      cd11897
      Location:458
      SH3_SNX18; Src Homology 3 domain of Sorting nexin 18

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      113728715..113755100 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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