Format

Send to:

Choose Destination
    • Showing Current items.

    Kpna3 karyopherin (importin) alpha 3 [ Mus musculus (house mouse) ]

    Gene ID: 16648, updated on 25-Nov-2021

    Summary

    Official Symbol
    Kpna3provided by MGI
    Official Full Name
    karyopherin (importin) alpha 3provided by MGI
    Primary source
    MGI:MGI:1100863
    See related
    Ensembl:ENSMUSG00000021929
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IPOA4
    Expression
    Ubiquitous expression in placenta adult (RPKM 19.9), CNS E18 (RPKM 18.5) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Kpna3 in Genome Data Viewer
    Location:
    14; 14 D1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (61602635..61677396, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (61365186..61439947, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (61984023..62058784, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene 5461 Neighboring gene predicted gene, 25716 Neighboring gene emopamil binding protein-like Neighboring gene ribosomal protein S12, pseudogene 2 Neighboring gene predicted gene, 41169

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nuclear import signal receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nuclear localization sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein C-terminus binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in NLS-bearing protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of NLS-dependent protein nuclear import complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    importin subunit alpha-4
    Names
    importin alpha 4
    importin alpha Q2
    importin subunit alpha-3
    karyopherin subunit alpha-3
    qip2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008466.5NP_032492.1  importin subunit alpha-4

      See identical proteins and their annotated locations for NP_032492.1

      Status: VALIDATED

      Source sequence(s)
      AC154435, AK049373, AV581906
      Consensus CDS
      CCDS36942.1
      UniProtKB/Swiss-Prot
      O35344
      UniProtKB/TrEMBL
      Q543M7
      Related
      ENSMUSP00000022496.8, ENSMUST00000022496.9
      Conserved Domains (2) summary
      COG5064
      Location:7521
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:244269
      ARM; armadillo repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      61602635..61677396 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center