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    Kif4 kinesin family member 4 [ Mus musculus (house mouse) ]

    Gene ID: 16571, updated on 23-Jun-2021

    Summary

    Official Symbol
    Kif4provided by MGI
    Official Full Name
    kinesin family member 4provided by MGI
    Primary source
    MGI:MGI:108389
    See related
    Ensembl:ENSMUSG00000034311
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kn; Kns4; AI323435; D330050K22Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 10.5), liver E14 (RPKM 7.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Kif4 in Genome Data Viewer
    Location:
    X C3; X 43.72 cM
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (99669671..99770877)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (100626065..100727271)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (97821404..97922610)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene pyrimidinergic receptor P2Y, G-protein coupled, 4 Neighboring gene arrestin 3, retinal Neighboring gene PDZ domain containing 11 Neighboring gene predicted gene, 52438 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene predicted gene 14902

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic spindle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    chromosome-associated kinesin KIF4
    Names
    N-5 kinesin
    chromokinesin
    kinesin heavy chain member 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008446.2NP_032472.2  chromosome-associated kinesin KIF4

      See identical proteins and their annotated locations for NP_032472.2

      Status: VALIDATED

      Source sequence(s)
      BB091691, BC050946, CF742002
      Consensus CDS
      CCDS30305.1
      UniProtKB/Swiss-Prot
      P33174
      Related
      ENSMUSP00000048383.4, ENSMUST00000048962.4
      Conserved Domains (4) summary
      smart00129
      Location:9344
      KISc; Kinesin motor, catalytic domain. ATPase
      COG0419
      Location:407995
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01372
      Location:8338
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      pfam05033
      Location:10701120
      Pre-SET; Pre-SET motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      99669671..99770877
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527855.5XP_006527918.1  chromosome-associated kinesin KIF4 isoform X1

      Conserved Domains (3) summary
      COG0419
      Location:407987
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01372
      Location:8338
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      pfam05033
      Location:10451087
      Pre-SET; Pre-SET motif
    2. XM_011247528.4XP_011245830.1  chromosome-associated kinesin KIF4 isoform X2

      See identical proteins and their annotated locations for XP_011245830.1

      Conserved Domains (3) summary
      COG0419
      Location:18606
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      TIGR02169
      Location:173459
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam05033
      Location:689731
      Pre-SET; Pre-SET motif
    3. XM_017318397.3XP_017173886.1  chromosome-associated kinesin KIF4 isoform X3

      Conserved Domains (2) summary
      COG0419
      Location:44518
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam05033
      Location:601643
      Pre-SET; Pre-SET motif
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