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    Kif4 kinesin family member 4 [ Mus musculus (house mouse) ]

    Gene ID: 16571, updated on 28-Oct-2018

    Summary

    Official Symbol
    Kif4provided by MGI
    Official Full Name
    kinesin family member 4provided by MGI
    Primary source
    MGI:MGI:108389
    See related
    Ensembl:ENSMUSG00000034311 Vega:OTTMUSG00000018285
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kns4; AI323435; D330050K22Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 10.5), liver E14 (RPKM 7.2) and 9 other tissues See more
    Orthologs

    Genomic context

    See Kif4 in Genome Data Viewer
    Location:
    X C3; X 43.72 cM
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (100626065..100727271)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (97821404..97922610)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene arrestin 3, retinal Neighboring gene PDZ domain containing 11 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene predicted gene 14902

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle midzone assembly ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    chromosome-associated kinesin KIF4
    Names
    N-5 kinesin
    chromokinesin
    kinesin heavy chain member 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008446.2NP_032472.2  chromosome-associated kinesin KIF4

      See identical proteins and their annotated locations for NP_032472.2

      Status: VALIDATED

      Source sequence(s)
      BB091691, BC050946, CF742002
      Consensus CDS
      CCDS30305.1
      UniProtKB/Swiss-Prot
      P33174
      Related
      ENSMUSP00000048383.3, OTTMUSP00000019864, ENSMUST00000048962.3, OTTMUST00000044183
      Conserved Domains (4) summary
      smart00129
      Location:9344
      KISc; Kinesin motor, catalytic domain. ATPase
      COG0419
      Location:407995
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01372
      Location:8338
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      pfam05033
      Location:10701120
      Pre-SET; Pre-SET motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      100626065..100727271
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527855.3XP_006527918.1  chromosome-associated kinesin KIF4 isoform X1

      Conserved Domains (4) summary
      smart00129
      Location:9344
      KISc; Kinesin motor, catalytic domain. ATPase
      COG0419
      Location:407987
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01372
      Location:8338
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      pfam05033
      Location:10371087
      Pre-SET; Pre-SET motif
    2. XM_011247528.2XP_011245830.1  chromosome-associated kinesin KIF4 isoform X2

      See identical proteins and their annotated locations for XP_011245830.1

      Conserved Domains (1) summary
      pfam05033
      Location:681731
      Pre-SET; Pre-SET motif
    3. XM_017318397.1XP_017173886.1  chromosome-associated kinesin KIF4 isoform X3

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