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    Kif11 kinesin family member 11 [ Mus musculus (house mouse) ]

    Gene ID: 16551, updated on 30-Oct-2018

    Summary

    Official Symbol
    Kif11provided by MGI
    Official Full Name
    kinesin family member 11provided by MGI
    Primary source
    MGI:MGI:1098231
    See related
    Ensembl:ENSMUSG00000012443
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Eg5; Kif8; Kifl1; Knsl1
    Expression
    Biased expression in CNS E11.5 (RPKM 30.5), liver E14 (RPKM 27.0) and 10 other tissues See more
    Orthologs

    Genomic context

    See Kif11 in Genome Data Viewer
    Location:
    19; 19 C2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (37376403..37421859)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (37450893..37496349)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4931408D14 gene Neighboring gene insulin degrading enzyme Neighboring gene ribosomal protein L10, pseudogene 6 Neighboring gene mortality factor 4 like 1 pseudogene Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene hematopoietically expressed homeobox Neighboring gene RIKEN cDNA 1700122C19 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATP-dependent microtubule motor activity, plus-end-directed IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ATPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic centrosome separation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of mitotic centrosome separation ISO
    Inferred from Sequence Orthology
    more info
     
    spindle assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spindle organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spindle ISO
    Inferred from Sequence Orthology
    more info
     
    spindle microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    kinesin-like protein KIF11
    Names
    kinesin-like 1
    kinesin-related motor protein Eg5

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010615.2NP_034745.1  kinesin-like protein KIF11

      See identical proteins and their annotated locations for NP_034745.1

      Status: VALIDATED

      Source sequence(s)
      BC060670, BY097786, CJ206639
      Consensus CDS
      CCDS29777.1
      UniProtKB/Swiss-Prot
      Q6P9P6
      Related
      ENSMUSP00000012587.3, ENSMUST00000012587.3
      Conserved Domains (3) summary
      smart00129
      Location:17365
      KISc; Kinesin motor, catalytic domain. ATPase
      cd01364
      Location:15367
      KISc_BimC_Eg5; Kinesin motor domain, BimC/Eg5 spindle pole proteins
      pfam13931
      Location:9151047
      Microtub_bind; Kinesin-associated microtubule-binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      37376403..37421859
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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