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    Itpr1 inositol 1,4,5-trisphosphate receptor 1 [ Mus musculus (house mouse) ]

    Gene ID: 16438, updated on 5-Sep-2021

    Summary

    Official Symbol
    Itpr1provided by MGI
    Official Full Name
    inositol 1,4,5-trisphosphate receptor 1provided by MGI
    Primary source
    MGI:MGI:96623
    See related
    Ensembl:ENSMUSG00000030102
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    I; o; IP; Pc; wb; Itp; P40; Pcp; opt; Ip3r; P400; Pcp1; wblo; IP3R1; Pcp-1; D6Pas2; IP3R 1; InsP3R; Itpr-1; Gm10429; insP3R1
    Expression
    Biased expression in cerebellum adult (RPKM 104.2), cortex adult (RPKM 29.7) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Itpr1 in Genome Data Viewer
    Location:
    6 E1- E2; 6 49.74 cM
    Exon count:
    65
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (108190044..108528077)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (108213083..108551116)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (108163090..108501108)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36, pseudogene 12 Neighboring gene sulfatase modifying factor 1 Neighboring gene predicted gene, 38872 Neighboring gene predicted gene, 35165 Neighboring gene microRNA 7661 Neighboring gene predicted gene, 44040 Neighboring gene RIKEN cDNA 0610040F04 gene Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 pseudogene Neighboring gene basic helix-loop-helix family, member e40

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables calcium channel inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium-release channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables inositol 1,4,5 trisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels EXP
    Inferred from Experiment
    more info
    PubMed 
    enables inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables phosphatidylinositol binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein domain specific binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within calcium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to cAMP ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within endoplasmic reticulum calcium ion homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in epithelial fluid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in liver regeneration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of calcium-mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of neuron death ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of calcium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of hepatocyte proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within post-embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in release of sequestered calcium ion into cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in release of sequestered calcium ion into cytosol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in release of sequestered calcium ion into cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to hypoxia IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to hypoxia ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within voluntary musculoskeletal movement IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Schaffer collateral - CA1 synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    located_in Schaffer collateral - CA1 synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    part_of calcineurin complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasmic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum TAS
    Traceable Author Statement
    more info
    PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in platelet dense granule membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in platelet dense tubular network ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in sarcoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in sarcoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in sarcoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in secretory granule membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in secretory granule membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    located_in synaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    inositol 1,4,5-trisphosphate receptor type 1
    Names
    IP3 receptor
    InsP>3<R type I
    Purkinje cell protein 1
    inositol 1,4,5-trisphosphate-binding protein P400
    opisthotonus
    protein PCD-6
    type 1 InsP3 receptor
    type 1 inositol 1,4,5-trisphosphate receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010585.5NP_034715.3  inositol 1,4,5-trisphosphate receptor type 1

      See identical proteins and their annotated locations for NP_034715.3

      Status: VALIDATED

      Source sequence(s)
      AC156506, AK044776, AK047719, AK049015, AK137477, BU705754, CB521690, CF168791, CF539692, CF744794, CJ236273, CK636937, CN459019, CN692248, DN176734, DV652411, M21530
      Consensus CDS
      CCDS51869.1
      UniProtKB/Swiss-Prot
      P11881
      UniProtKB/TrEMBL
      Q3UVA1, Q8BQN0, Q8C7X9, Q8C8N0
      Related
      ENSMUSP00000032192.7, ENSMUST00000032192.9
      Conserved Domains (6) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:23412600
      Ion_trans; Ion transport protein
      pfam01365
      Location:476665
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19642069
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      108190044..108528077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505623.1XP_006505686.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X1

      Conserved Domains (5) summary
      pfam00520
      Location:23222609
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19732078
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    2. XM_017321407.1XP_017176896.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X2

      Conserved Domains (5) summary
      pfam00520
      Location:23212608
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19722077
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    3. XM_006505627.1XP_006505690.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X6

      Conserved Domains (5) summary
      pfam00520
      Location:23052592
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19562061
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    4. XM_006505624.1XP_006505687.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X3

      Conserved Domains (5) summary
      pfam00520
      Location:23112598
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19622067
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    5. XM_006505625.1XP_006505688.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X4

      Conserved Domains (5) summary
      pfam00520
      Location:23102597
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19612066
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    6. XM_006505632.1XP_006505695.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X11

      Conserved Domains (5) summary
      pfam00520
      Location:22942581
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19452050
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    7. XM_006505628.1XP_006505691.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X7

      Conserved Domains (5) summary
      pfam00520
      Location:22992586
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19502055
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    8. XM_006505629.1XP_006505692.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X8

      Conserved Domains (5) summary
      pfam00520
      Location:22982585
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19492054
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    9. XM_006505633.1XP_006505696.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X12

      Conserved Domains (5) summary
      pfam00520
      Location:22822569
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19332038
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    10. XM_017321408.1XP_017176897.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X15

      UniProtKB/Swiss-Prot
      P11881
      Related
      ENSMUSP00000144880.2, ENSMUST00000203615.3
      Conserved Domains (5) summary
      pfam00520
      Location:23122599
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19632068
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    11. XM_006505636.1XP_006505699.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X18

      UniProtKB/Swiss-Prot
      P11881
      Conserved Domains (5) summary
      pfam00520
      Location:22732560
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19242029
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    12. XM_006505626.1XP_006505689.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X5

      Conserved Domains (5) summary
      pfam00520
      Location:23072594
      Ion_trans; Ion transport protein
      pfam01365
      Location:459655
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19582063
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    13. XM_017321409.1XP_017176898.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X16

      Conserved Domains (5) summary
      pfam00520
      Location:23062593
      Ion_trans; Ion transport protein
      pfam01365
      Location:459655
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19572062
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    14. XM_006505630.1XP_006505693.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X9

      UniProtKB/Swiss-Prot
      P11881
      Conserved Domains (5) summary
      pfam00520
      Location:22982585
      Ion_trans; Ion transport protein
      pfam01365
      Location:459655
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19492054
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    15. XM_017321410.1XP_017176899.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X17

      UniProtKB/Swiss-Prot
      P11881
      Conserved Domains (5) summary
      pfam00520
      Location:22972584
      Ion_trans; Ion transport protein
      pfam01365
      Location:459655
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19482053
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    16. XM_006505637.1XP_006505700.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X19

      UniProtKB/Swiss-Prot
      P11881
      Conserved Domains (5) summary
      pfam00520
      Location:22582545
      Ion_trans; Ion transport protein
      pfam01365
      Location:459655
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19092014
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    17. XM_006505631.3XP_006505694.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X10

      Conserved Domains (5) summary
      pfam00520
      Location:23222609
      Ion_trans; Ion transport protein
      pfam01365
      Location:474670
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19732078
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    18. XM_036165883.1XP_036021776.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X14

    19. XM_030255199.1XP_030111059.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X13

      Conserved Domains (5) summary
      pfam00520
      Location:22602547
      Ion_trans; Ion transport protein
      pfam01365
      Location:412608
      RYDR_ITPR; RIH domain
      pfam02815
      Location:170371
      MIR; MIR domain
      pfam08454
      Location:19112016
      RIH_assoc; RyR and IP3R Homology associated
      cl19745
      Location:1163
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
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