Format

Send to:

Choose Destination
    • Showing Current items.

    Eif3e eukaryotic translation initiation factor 3, subunit E [ Mus musculus (house mouse) ]

    Gene ID: 16341, updated on 31-Jan-2019

    Summary

    Official Symbol
    Eif3eprovided by MGI
    Official Full Name
    eukaryotic translation initiation factor 3, subunit Eprovided by MGI
    Primary source
    MGI:MGI:99257
    See related
    Ensembl:ENSMUSG00000022336
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Int6; 48kDa; Eif3s6; eIF3-p46; eIF3-p48
    Expression
    Broad expression in CNS E11.5 (RPKM 59.0), placenta adult (RPKM 52.0) and 22 other tissues See more
    Orthologs

    Genomic context

    See Eif3e in Genome Data Viewer
    Location:
    15 B3.2; 15 16.73 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (43250040..43282736, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (43081586..43114282, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene R-spondin 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 33743 Neighboring gene predicted gene 10373

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to translation initiation factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to translation initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of translation ISO
    Inferred from Sequence Orthology
    more info
     
    translation IEA
    Inferred from Electronic Annotation
    more info
     
    translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    translational initiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    translational initiation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    colocalizes_with PML body ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    eukaryotic translation initiation factor 3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    eukaryotic translation initiation factor 3 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    eukaryotic translation initiation factor 3 complex ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 3 subunit E
    Names
    MMTV integration site 6
    eIF3e
    eukaryotic translation initiation factor 3, subunit 6 48kDa
    mammary tumor integration site 6
    mammary tumor-associated protein INT-6
    viral integration site protein INT-6

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008388.2NP_032414.1  eukaryotic translation initiation factor 3 subunit E

      See identical proteins and their annotated locations for NP_032414.1

      Status: VALIDATED

      Source sequence(s)
      AA982184, AK161650, BY114098
      Consensus CDS
      CCDS27452.1
      UniProtKB/Swiss-Prot
      P60229
      UniProtKB/TrEMBL
      Q3UIG0
      Related
      ENSMUSP00000022960.2, ENSMUST00000022960.3
      Conserved Domains (2) summary
      pfam01399
      Location:290394
      PCI; PCI domain
      pfam09440
      Location:5137
      eIF3_N; eIF3 subunit 6 N terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      43250040..43282736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center