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    OR7D2 olfactory receptor family 7 subfamily D member 2 [ Homo sapiens (human) ]

    Gene ID: 162998, updated on 17-Jun-2024

    Summary

    Official Symbol
    OR7D2provided by HGNC
    Official Full Name
    olfactory receptor family 7 subfamily D member 2provided by HGNC
    Primary source
    HGNC:HGNC:8378
    See related
    Ensembl:ENSG00000188000 AllianceGenome:HGNC:8378
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR19-4; OR19-10; HTPCRH03
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR7D2 in Genome Data Viewer
    Location:
    19p13.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (9178979..9188818)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (9305174..9315012)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9289655..9299494)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily G member 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13925 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13926 Neighboring gene zinc finger protein 317 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:9270512-9271012 Neighboring gene elongin C pseudogene 29 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr19:9300121-9300643 Neighboring gene olfactory receptor family 7 subfamily E member 16 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 25 pseudogene

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ38149

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 7D2
    Names
    olfactory receptor 19-4
    olfactory receptor OR19-10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386112.1NP_001373041.1  olfactory receptor 7D2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC011464
      Consensus CDS
      CCDS32900.1
      UniProtKB/Swiss-Prot
      Q6IFJ7, Q8N133, Q96RA2
      UniProtKB/TrEMBL
      A0A126GVY4
      Related
      ENSP00000492939.1, ENST00000642043.1
      Conserved Domains (1) summary
      cd15234
      Location:25301
      7tmA_OR7-like; olfactory receptor family 7 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    2. NM_175883.4NP_787079.1  olfactory receptor 7D2

      See identical proteins and their annotated locations for NP_787079.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC011464
      Consensus CDS
      CCDS32900.1
      UniProtKB/Swiss-Prot
      Q6IFJ7, Q8N133, Q96RA2
      UniProtKB/TrEMBL
      A0A126GVY4
      Related
      ENSP00000493200.1, ENST00000641288.2
      Conserved Domains (1) summary
      cd15234
      Location:25301
      7tmA_OR7-like; olfactory receptor family 7 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      9178979..9188818
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047438317.1XP_047294273.1  olfactory receptor 7D2 isoform X1

      UniProtKB/Swiss-Prot
      Q6IFJ7, Q8N133, Q96RA2
      UniProtKB/TrEMBL
      A0A126GVY4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      9305174..9315012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054320058.1XP_054176033.1  olfactory receptor 7D2 isoform X1

      UniProtKB/Swiss-Prot
      Q6IFJ7, Q8N133, Q96RA2
      UniProtKB/TrEMBL
      A0A126GVY4