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    BRD10 bromodomain containing 10 [ Homo sapiens (human) ]

    Gene ID: 158358, updated on 5-May-2024

    Summary

    Official Symbol
    BRD10provided by HGNC
    Official Full Name
    bromodomain containing 10provided by HGNC
    Primary source
    HGNC:HGNC:23378
    See related
    Ensembl:ENSG00000183354 AllianceGenome:HGNC:23378
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KIAA2026
    Expression
    Ubiquitous expression in testis (RPKM 4.2), thyroid (RPKM 2.9) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See BRD10 in Genome Data Viewer
    Location:
    9p24.1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (5878834..6008482, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (5881968..6013620, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (5919022..6008482, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene RIC1 homolog, RAB6A GEF complex partner 1 Neighboring gene uncharacterized LOC124902115 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:5762408-5763607 Neighboring gene endoplasmic reticulum metallopeptidase 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19755 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19756 Neighboring gene Sharpr-MPRA regulatory region 2314 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28177 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28178 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28179 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19757 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:5879621-5880122 Neighboring gene small nucleolar RNA U13 Neighboring gene adenylate kinase 4 pseudogene 4 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr9:5909826-5911025 Neighboring gene melan-A Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19758 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28180 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19759 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:6007511-6008012 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:6008013-6008512 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28181 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19762 Neighboring gene microRNA 4665 Neighboring gene RAN binding protein 6 Neighboring gene uncharacterized LOC124902116

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    uncharacterized bromodomain-containing protein 10; uncharacterized protein KIAA2026

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017969.3NP_001017969.2  uncharacterized bromodomain-containing protein 10

      See identical proteins and their annotated locations for NP_001017969.2

      Status: VALIDATED

      Source sequence(s)
      AL162384, AL365360, BC108654, DY655479
      UniProtKB/Swiss-Prot
      A8MTP2, B9EGW7, Q4VXA2, Q5HYC2, Q8IVE5
      Related
      ENSP00000382815.3, ENST00000399933.8
      Conserved Domains (3) summary
      cd04369
      Location:137193
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      pfam05672
      Location:253292
      MAP7; MAP7 (E-MAP-115) family
      pfam06936
      Location:225287
      Selenoprotein_S; Selenoprotein S (SelS)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      5878834..6008482 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011517760.4XP_011516062.1  uncharacterized protein KIAA2026 isoform X3

      See identical proteins and their annotated locations for XP_011516062.1

      Conserved Domains (4) summary
      cd04369
      Location:137193
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      PHA03255
      Location:16681825
      PHA03255; BDLF3; Provisional
      pfam05109
      Location:11801760
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam06936
      Location:225287
      Selenoprotein_S; Selenoprotein S (SelS)
    2. XM_011517759.4XP_011516061.1  uncharacterized protein KIAA2026 isoform X3

      See identical proteins and their annotated locations for XP_011516061.1

      Conserved Domains (4) summary
      cd04369
      Location:137193
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      PHA03255
      Location:16681825
      PHA03255; BDLF3; Provisional
      pfam05109
      Location:11801760
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam06936
      Location:225287
      Selenoprotein_S; Selenoprotein S (SelS)
    3. XM_047422861.1XP_047278817.1  uncharacterized protein KIAA2026 isoform X6

    4. XM_017014331.3XP_016869820.1  uncharacterized protein KIAA2026 isoform X2

    5. XM_005251385.4XP_005251442.1  uncharacterized protein KIAA2026 isoform X1

      UniProtKB/Swiss-Prot
      Q5HYC2
      Related
      ENSP00000370870.2, ENST00000381461.6
      Conserved Domains (3) summary
      cd04369
      Location:137193
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      pfam05672
      Location:253292
      MAP7; MAP7 (E-MAP-115) family
      pfam06936
      Location:225287
      Selenoprotein_S; Selenoprotein S (SelS)
    6. XM_047422860.1XP_047278816.1  uncharacterized protein KIAA2026 isoform X5

    7. XM_024447429.2XP_024303197.1  uncharacterized protein KIAA2026 isoform X4

    8. XM_011517761.3XP_011516063.1  uncharacterized protein KIAA2026 isoform X5

      See identical proteins and their annotated locations for XP_011516063.1

      UniProtKB/Swiss-Prot
      Q5HYC2
    9. XM_047422862.1XP_047278818.1  uncharacterized protein KIAA2026 isoform X7

    RNA

    1. XR_007061251.1 RNA Sequence

    2. XR_007061249.1 RNA Sequence

    3. XR_007061250.1 RNA Sequence

    4. XR_007061252.1 RNA Sequence

    5. XR_001746198.3 RNA Sequence

    6. XR_001746203.3 RNA Sequence

    7. XR_001746207.3 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      5881968..6013620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054362141.1XP_054218116.1  uncharacterized protein KIAA2026 isoform X3

    2. XM_054362145.1XP_054218120.1  uncharacterized protein KIAA2026 isoform X6

    3. XM_054362140.1XP_054218115.1  uncharacterized protein KIAA2026 isoform X1

    4. XM_054362143.1XP_054218118.1  uncharacterized protein KIAA2026 isoform X5

    5. XM_054362142.1XP_054218117.1  uncharacterized protein KIAA2026 isoform X4

    6. XM_054362144.1XP_054218119.1  uncharacterized protein KIAA2026 isoform X5

    7. XM_054362146.1XP_054218121.1  uncharacterized protein KIAA2026 isoform X7

    RNA

    1. XR_008487947.1 RNA Sequence

    2. XR_008487946.1 RNA Sequence

    3. XR_008487948.1 RNA Sequence

    4. XR_008487949.1 RNA Sequence