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    Elavl2 ELAV like RNA binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 15569, updated on 21-Sep-2021

    Summary

    Official Symbol
    Elavl2provided by MGI
    Official Full Name
    ELAV like RNA binding protein 1provided by MGI
    Primary source
    MGI:MGI:1100887
    See related
    Ensembl:ENSMUSG00000008489
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hub; mel-; mel-N1
    Expression
    Biased expression in whole brain E14.5 (RPKM 12.9), CNS E18 (RPKM 11.4) and 5 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Elavl2 in Genome Data Viewer
    Location:
    4 C5; 4 42.36 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (91099770..91288407, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (91211533..91400108, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (90917457..91066675, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12643 Neighboring gene within bgcn homolog pseudogene Neighboring gene non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase) pseudogene Neighboring gene microRNA 6402 Neighboring gene predicted gene, 40202 Neighboring gene heat shock protein 1 (chaperonin) pseudogene 21

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to leukemia inhibitory factor IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ELAV-like protein 2
    Names
    ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
    ELAV-like neuronal protein 1
    HU-antigen B
    nervous system-specific RNA-binding protein Mel-N1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177883.2NP_001171354.1  ELAV-like protein 2 isoform 4

      See identical proteins and their annotated locations for NP_001171354.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alterntae exon in the 5' end, which causes translation initiation at a downstream start codon, compared to variant 5. The resulting isoform (4) has a shorter N-terminus when it is compared to isoform 5.
      Source sequence(s)
      AK141919, AL954140, BC046598, BY284852, CO038990
      Consensus CDS
      CCDS51230.1
      UniProtKB/TrEMBL
      Q3UR02
      Related
      ENSMUSP00000102741.4, ENSMUST00000107124.10
      Conserved Domains (1) summary
      TIGR01661
      Location:36358
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    2. NM_001347149.2NP_001334078.1  ELAV-like protein 2 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) encodes isoform 5.
      Source sequence(s)
      AL837505, AL954140, BY284852, CO038990
      Consensus CDS
      CCDS84753.1
      UniProtKB/TrEMBL
      B1AXZ4
      Related
      ENSMUSP00000102737.2, ENSMUST00000107120.8
      Conserved Domains (1) summary
      TIGR01661
      Location:65387
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    3. NM_001357188.1NP_001344117.1  ELAV-like protein 2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AK141919, AL954140, BC046598, BI985114, BY284852, CB524847, CO038990
      Consensus CDS
      CCDS89779.1
      Conserved Domains (1) summary
      TIGR01661
      Location:65388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    4. NM_001357189.1NP_001344118.1  ELAV-like protein 2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AK141919, AL954140, BC046598, BI985114, BY129136, CB524847, CO038990
      Consensus CDS
      CCDS89779.1
      Related
      ENSMUSP00000102733.3, ENSMUST00000107116.9
      Conserved Domains (1) summary
      TIGR01661
      Location:65388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    5. NM_001374236.1NP_001361165.1  ELAV-like protein 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL837505, AL954140
      Conserved Domains (1) summary
      TIGR01661
      Location:65387
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    6. NM_001374237.1NP_001361166.1  ELAV-like protein 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL837505, AL954140
      Consensus CDS
      CCDS84753.1
      Conserved Domains (1) summary
      TIGR01661
      Location:65387
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    7. NM_001374238.1NP_001361167.1  ELAV-like protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL837505, AL954140
      Consensus CDS
      CCDS51230.1
      Conserved Domains (1) summary
      TIGR01661
      Location:36358
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    8. NM_001374696.1NP_001361625.1  ELAV-like protein 2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL837505, AL954140
      Consensus CDS
      CCDS89778.1
      Related
      ENSMUSP00000102735.2, ENSMUST00000107118.8
      Conserved Domains (1) summary
      TIGR01661
      Location:65375
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    9. NM_010486.2NP_034616.1  ELAV-like protein 2 isoform 2

      See identical proteins and their annotated locations for NP_034616.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple differences, one of which causes translation initiation at a downstream start codon, compared to variant 5. The resulting isoform (2) has a shorter N-terminus and has one additional aa in the C-terminus when it is compared to isoform 5.
      Source sequence(s)
      BC046598, BY129136, U29088
      Consensus CDS
      CCDS18355.1
      UniProtKB/Swiss-Prot
      Q60899
      UniProtKB/TrEMBL
      Q564D8, Q80UJ0
      Related
      ENSMUSP00000008633.9, ENSMUST00000008633.15
      Conserved Domains (1) summary
      TIGR01661
      Location:36359
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    10. NM_207685.2NP_997568.1  ELAV-like protein 2 isoform 1

      See identical proteins and their annotated locations for NP_997568.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR and coding sequence compared to variant 5. The resulting isoform (1) has a shorter and distinct N-terminus compared to isoform 5.
      Source sequence(s)
      AL954140, BC046598, BC058393, CO038990
      Consensus CDS
      CCDS18354.1
      UniProtKB/TrEMBL
      Q80Y51
      Related
      ENSMUSP00000099863.4, ENSMUST00000102799.10
      Conserved Domains (1) summary
      TIGR01661
      Location:50372
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    11. NM_207686.1NP_997569.1  ELAV-like protein 2 isoform 3

      See identical proteins and their annotated locations for NP_997569.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has multiple differences, one of which causes translation initiation at a downstream start codon, compared to variant 5. The resulting isoform (3) has a shorter N-terminus and has one additional aa in the C-terminus when it is compared to isoform 5.
      Source sequence(s)
      BC046598, BY129136
      Consensus CDS
      CCDS18356.1
      UniProtKB/TrEMBL
      Q80UJ0
      Related
      ENSMUSP00000102727.2, ENSMUST00000107110.8
      Conserved Domains (1) summary
      TIGR01661
      Location:36346
      ELAV_HUD_SF; ELAV/HuD family splicing factor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      91099770..91288407 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163717.1XP_036019610.1  ELAV-like protein 2 isoform X12

      Conserved Domains (1) summary
      TIGR01661
      Location:50372
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    2. XM_036163715.1XP_036019608.1  ELAV-like protein 2 isoform X8

      Conserved Domains (1) summary
      TIGR01661
      Location:65387
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    3. XM_006502784.5XP_006502847.1  ELAV-like protein 2 isoform X7

      See identical proteins and their annotated locations for XP_006502847.1

      UniProtKB/TrEMBL
      B1AXZ5
      Conserved Domains (1) summary
      TIGR01661
      Location:65388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    4. XM_006502788.5XP_006502851.1  ELAV-like protein 2 isoform X13

      Conserved Domains (1) summary
      TIGR01661
      Location:49372
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    5. XM_006502787.5XP_006502850.1  ELAV-like protein 2 isoform X11

      See identical proteins and their annotated locations for XP_006502850.1

      Conserved Domains (1) summary
      TIGR01661
      Location:50373
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    6. XM_030253232.2XP_030109092.1  ELAV-like protein 2 isoform X7

      Conserved Domains (1) summary
      TIGR01661
      Location:65388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    7. XM_036163714.1XP_036019607.1  ELAV-like protein 2 isoform X8

      Conserved Domains (1) summary
      TIGR01661
      Location:65387
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    8. XM_036163713.1XP_036019606.1  ELAV-like protein 2 isoform X7

      Conserved Domains (1) summary
      TIGR01661
      Location:65388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    9. XM_036163727.1XP_036019620.1  ELAV-like protein 2 isoform X17

      Related
      ENSMUSP00000102728.3, ENSMUST00000107111.9
      Conserved Domains (1) summary
      TIGR01661
      Location:36345
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    10. XM_036163725.1XP_036019618.1  ELAV-like protein 2 isoform X16

      Conserved Domains (1) summary
      TIGR01661
      Location:36346
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    11. XM_036163722.1XP_036019615.1  ELAV-like protein 2 isoform X15

      Conserved Domains (1) summary
      TIGR01661
      Location:36358
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    12. XM_036163718.1XP_036019611.1  ELAV-like protein 2 isoform X14

      Conserved Domains (1) summary
      TIGR01661
      Location:36359
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    13. XM_036163716.1XP_036019609.1  ELAV-like protein 2 isoform X10

      Conserved Domains (1) summary
      TIGR01661
      Location:65375
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    14. XM_030253243.2XP_030109103.1  ELAV-like protein 2 isoform X16

      Conserved Domains (1) summary
      TIGR01661
      Location:36346
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    15. XM_030253239.2XP_030109099.1  ELAV-like protein 2 isoform X15

      Conserved Domains (1) summary
      TIGR01661
      Location:36358
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    16. XM_006502790.4XP_006502853.1  ELAV-like protein 2 isoform X14

      See identical proteins and their annotated locations for XP_006502853.1

      UniProtKB/Swiss-Prot
      Q60899
      UniProtKB/TrEMBL
      Q564D8
      Conserved Domains (1) summary
      TIGR01661
      Location:36359
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    17. XM_017319989.3XP_017175478.1  ELAV-like protein 2 isoform X9

      Conserved Domains (1) summary
      TIGR01661
      Location:64387
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    18. XM_030253233.2XP_030109093.1  ELAV-like protein 2 isoform X7

      Conserved Domains (1) summary
      TIGR01661
      Location:65388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    19. XM_006502785.5XP_006502848.1  ELAV-like protein 2 isoform X7

      See identical proteins and their annotated locations for XP_006502848.1

      UniProtKB/TrEMBL
      B1AXZ5
      Conserved Domains (1) summary
      TIGR01661
      Location:65388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    20. XM_036163721.1XP_036019614.1  ELAV-like protein 2 isoform X14

      Conserved Domains (1) summary
      TIGR01661
      Location:36359
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    21. XM_030253236.2XP_030109096.1  ELAV-like protein 2 isoform X8

      Conserved Domains (1) summary
      TIGR01661
      Location:65387
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    22. XM_036163724.1XP_036019617.1  ELAV-like protein 2 isoform X15

      Conserved Domains (1) summary
      TIGR01661
      Location:36358
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    23. XM_036163729.1XP_036019622.1  ELAV-like protein 2 isoform X18

      Conserved Domains (1) summary
      TIGR01661
      Location:206335
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    24. XM_036163728.1XP_036019621.1  ELAV-like protein 2 isoform X18

      Conserved Domains (1) summary
      TIGR01661
      Location:206335
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    25. XM_006502779.5XP_006502842.1  ELAV-like protein 2 isoform X3

      Conserved Domains (1) summary
      TIGR01661
      Location:205528
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    26. XM_036163711.1XP_036019604.1  ELAV-like protein 2 isoform X5

      Conserved Domains (1) summary
      TIGR01661
      Location:206516
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    27. XM_036163712.1XP_036019605.1  ELAV-like protein 2 isoform X6

      Conserved Domains (1) summary
      TIGR01661
      Location:206515
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    28. XM_036163726.1XP_036019619.1  ELAV-like protein 2 isoform X16

      Conserved Domains (1) summary
      TIGR01661
      Location:36346
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    29. XM_030253231.2XP_030109091.1  ELAV-like protein 2 isoform X4

      Conserved Domains (1) summary
      TIGR01661
      Location:205527
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    30. XM_036163709.1XP_036019602.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    31. XM_036163708.1XP_036019601.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    32. XM_036163704.1XP_036019597.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    33. XM_036163706.1XP_036019599.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    34. XM_036163707.1XP_036019600.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    35. XM_036163703.1XP_036019596.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    36. XM_036163700.1XP_036019593.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    37. XM_036163705.1XP_036019598.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    38. XM_036163702.1XP_036019595.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    39. XM_036163699.1XP_036019592.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    40. XM_036163701.1XP_036019594.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    41. XM_036163697.1XP_036019590.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    42. XM_036163698.1XP_036019591.1  ELAV-like protein 2 isoform X1

      Conserved Domains (1) summary
      TIGR01661
      Location:206529
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    43. XM_036163720.1XP_036019613.1  ELAV-like protein 2 isoform X14

      Conserved Domains (1) summary
      TIGR01661
      Location:36359
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    44. XM_036163710.1XP_036019603.1  ELAV-like protein 2 isoform X2

      Conserved Domains (1) summary
      TIGR01661
      Location:206528
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    45. XM_036163723.1XP_036019616.1  ELAV-like protein 2 isoform X15

      Conserved Domains (1) summary
      TIGR01661
      Location:36358
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    46. XM_030253241.2XP_030109101.1  ELAV-like protein 2 isoform X15

      Conserved Domains (1) summary
      TIGR01661
      Location:36358
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    47. XM_030253244.2XP_030109104.1  ELAV-like protein 2 isoform X16

      Conserved Domains (1) summary
      TIGR01661
      Location:36346
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    48. XM_006502791.4XP_006502854.1  ELAV-like protein 2 isoform X14

      See identical proteins and their annotated locations for XP_006502854.1

      UniProtKB/Swiss-Prot
      Q60899
      UniProtKB/TrEMBL
      Q564D8
      Conserved Domains (1) summary
      TIGR01661
      Location:36359
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    49. XM_017319987.3XP_017175476.1  ELAV-like protein 2 isoform X7

      UniProtKB/TrEMBL
      B1AXZ5
      Conserved Domains (1) summary
      TIGR01661
      Location:65388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    50. XM_030253237.2XP_030109097.1  ELAV-like protein 2 isoform X8

      Conserved Domains (1) summary
      TIGR01661
      Location:65387
      ELAV_HUD_SF; ELAV/HuD family splicing factor
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