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    Hnrnpl heterogeneous nuclear ribonucleoprotein L [ Mus musculus (house mouse) ]

    Gene ID: 15388, updated on 23-Jun-2021

    Summary

    Official Symbol
    Hnrnplprovided by MGI
    Official Full Name
    heterogeneous nuclear ribonucleoprotein Lprovided by MGI
    Primary source
    MGI:MGI:104816
    See related
    Ensembl:ENSMUSG00000015165
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H; Hnrpl; C79783; D830027H13Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 136.9), limb E14.5 (RPKM 90.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Hnrnpl in Genome Data Viewer
    Location:
    7; 7 B1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28507971..28521693)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28808546..28822268)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (29595909..29607285)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene sirtuin 2 Neighboring gene predicted gene, 19897 Neighboring gene Ras and Rab interactor-like Neighboring gene nuclear encoded tRNA lysine 24 (anticodon TTT) Neighboring gene enoyl coenzyme A hydratase 1, peroxisomal Neighboring gene lectin, galactose binding, soluble 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA CDS binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables pre-mRNA intronic binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription cis-regulatory region binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in pronucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    heterogeneous nuclear ribonucleoprotein L
    Names
    hnRNP L

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177301.5NP_796275.3  heterogeneous nuclear ribonucleoprotein L

      See identical proteins and their annotated locations for NP_796275.3

      Status: VALIDATED

      Source sequence(s)
      AI987696, AK006480, AK144684, BY309838, BY426285, CV561640
      Consensus CDS
      CCDS39864.2
      UniProtKB/Swiss-Prot
      Q8R081
      UniProtKB/TrEMBL
      Q3UMT7, Q9CVU5
      Related
      ENSMUSP00000049407.9, ENSMUST00000038572.15
      Conserved Domains (1) summary
      TIGR01649
      Location:97584
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      28507971..28521693
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539556.1XP_006539619.1  heterogeneous nuclear ribonucleoprotein L isoform X1

      See identical proteins and their annotated locations for XP_006539619.1

      Related
      ENSMUSP00000134734.2, ENSMUST00000174477.8
      Conserved Domains (1) summary
      TIGR01649
      Location:97621
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
    2. XM_006539558.4XP_006539621.1  heterogeneous nuclear ribonucleoprotein L isoform X3

      See identical proteins and their annotated locations for XP_006539621.1

      UniProtKB/Swiss-Prot
      Q8R081
      Related
      ENSMUSP00000133728.2, ENSMUST00000174548.8
      Conserved Domains (1) summary
      TIGR01649
      Location:97584
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
    3. XM_006539557.4XP_006539620.1  heterogeneous nuclear ribonucleoprotein L isoform X2

      Conserved Domains (1) summary
      TIGR01649
      Location:76600
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
    4. XM_006539559.4XP_006539622.1  heterogeneous nuclear ribonucleoprotein L isoform X4

      Related
      ENSMUSP00000133932.2, ENSMUST00000172529.8
      Conserved Domains (1) summary
      TIGR01649
      Location:76563
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
    5. XM_006539560.2XP_006539623.1  heterogeneous nuclear ribonucleoprotein L isoform X5

      Conserved Domains (1) summary
      TIGR01649
      Location:97291
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
    6. XM_036152696.1XP_036008589.1  heterogeneous nuclear ribonucleoprotein L isoform X6

      Conserved Domains (1) summary
      TIGR01649
      Location:97292
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family

    RNA

    1. XR_003946390.1 RNA Sequence

    2. XR_003946391.1 RNA Sequence

    3. XR_004934017.1 RNA Sequence

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