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    Hnrnpk heterogeneous nuclear ribonucleoprotein K [ Mus musculus (house mouse) ]

    Gene ID: 15387, updated on 28-Oct-2018

    Summary

    Official Symbol
    Hnrnpkprovided by MGI
    Official Full Name
    heterogeneous nuclear ribonucleoprotein Kprovided by MGI
    Primary source
    MGI:MGI:99894
    See related
    Ensembl:ENSMUSG00000021546 Vega:OTTMUSG00000035894
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    KBBP; NOVA; Hnrpk
    Summary
    The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including the nucleus, cytoplasm and mitochondria. This gene product is thought to interact with RNA, DNA, and protein, and is involved in multiple cellular processes, including transcription, chromatin remodeling, DNA damage response, signal transduction, mRNA splicing, export, and translation. Multiple transcript variants and protein isoforms exist, with some isoforms containing a unique C-terminus. There are four pseudogenes of this gene, found on chromosomes 2, 3, 7 and 13. [provided by RefSeq, Aug 2014]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 240.5), CNS E14 (RPKM 167.5) and 25 other tissues See more
    Orthologs

    Genomic context

    See Hnrnpk in Genome Data Viewer
    Location:
    13; 13 B1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (58391132..58403343, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (58493312..58503877, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene kinesin family member 27 Neighboring gene microRNA 6369 Neighboring gene RIKEN cDNA 2210016F16 gene Neighboring gene microRNA 7-1 Neighboring gene RecQ mediated genome instability 1 Neighboring gene predicted gene, 33875 Neighboring gene predicted gene, 40966

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102032

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    C-rich single-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II proximal promoter sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    actinin binding ISO
    Inferred from Sequence Orthology
    more info
     
    double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    heat shock protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    lamin binding ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA CDS binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    pre-mRNA 3'-splice site binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    proximal promoter sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    ribonucleoprotein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    single-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to forskolin ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to insulin stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cerebral cortex development ISO
    Inferred from Sequence Orthology
    more info
     
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    modulation of chemical synaptic transmission ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of branching morphogenesis of a nerve ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    ovarian follicle development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of RNA splicing ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of dendrite extension ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of dendritic spine development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of long-term synaptic potentiation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of low-density lipoprotein particle receptor biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein localization to cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of receptor-mediated endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of synapse maturation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of synaptic transmission ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of low-density lipoprotein particle clearance ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of postsynapse organization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    axon terminus ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    cell cortex ISO
    Inferred from Sequence Orthology
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    postsynapse ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    protein-DNA complex ISO
    Inferred from Sequence Orthology
    more info
     
    spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    heterogeneous nuclear ribonucleoprotein K

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001301340.1NP_001288269.1  heterogeneous nuclear ribonucleoprotein K isoform 1

      See identical proteins and their annotated locations for NP_001288269.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1).
      Source sequence(s)
      AK011428, AK160615, AV367088, BC089328, BE993983
      Consensus CDS
      CCDS79199.1
      UniProtKB/Swiss-Prot
      P61979
      UniProtKB/TrEMBL
      Q5FWJ5
      Related
      ENSMUSP00000153253.1, ENSMUST00000224182.1
      Conserved Domains (3) summary
      cd00105
      Location:389452
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    2. NM_001301341.1NP_001288270.1  heterogeneous nuclear ribonucleoprotein K isoform 1

      See identical proteins and their annotated locations for NP_001288270.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1, 2, and 3 encode the same isoform (1).
      Source sequence(s)
      AK078777, AV367088, BC089328, BE993983
      Consensus CDS
      CCDS79199.1
      UniProtKB/Swiss-Prot
      P61979
      UniProtKB/TrEMBL
      Q5FWJ5
      Related
      ENSMUSP00000112104.2, OTTMUSP00000050778, ENSMUST00000116403.8, OTTMUST00000092042
      Conserved Domains (3) summary
      cd00105
      Location:389452
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    3. NM_001301343.1NP_001288272.1  heterogeneous nuclear ribonucleoprotein K isoform 1

      See identical proteins and their annotated locations for NP_001288272.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1).
      Source sequence(s)
      AK166927, AV367088, BC089328, BE993983, BY794631
      Consensus CDS
      CCDS79199.1
      UniProtKB/Swiss-Prot
      P61979
      UniProtKB/TrEMBL
      Q5FWJ5
      Related
      ENSMUSP00000152935.1, ENSMUST00000225674.1
      Conserved Domains (3) summary
      cd00105
      Location:389452
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    4. NM_001301344.1NP_001288273.1  heterogeneous nuclear ribonucleoprotein K isoform 3

      See identical proteins and their annotated locations for NP_001288273.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks an in-frame exon compared to variant 1. It encodes isoform 3 which is shorter than isoform 1.
      Source sequence(s)
      AK011428, AK051313, AK151689, AK160615, AV367088, BC089328, BE993983
      Consensus CDS
      CCDS79198.1
      UniProtKB/Swiss-Prot
      P61979
      UniProtKB/TrEMBL
      B2M1R6, Q3U9Q3, Q5FWJ5
      Related
      ENSMUSP00000135647.1, OTTMUSP00000061593, ENSMUST00000177019.7, OTTMUST00000110426
      Conserved Domains (3) summary
      cd00105
      Location:365428
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:122186
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    5. NM_001301345.1NP_001288274.1  heterogeneous nuclear ribonucleoprotein K isoform 4

      See identical proteins and their annotated locations for NP_001288274.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks an in-frame exon and uses an alternative splice site in the 3' terminal exon, which results in a frameshift, compared to variant 1. It encodes isoform 4 which is shorter and has a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK011428, AK051313, AV367088, BC089328, BE993983
      Consensus CDS
      CCDS79197.1
      UniProtKB/Swiss-Prot
      P61979
      UniProtKB/TrEMBL
      Q5FWJ5
      Related
      ENSMUSP00000135354.1, OTTMUSP00000061594, ENSMUST00000176207.7, OTTMUST00000110427
      Conserved Domains (3) summary
      cd02396
      Location:122186
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam00013
      Location:365429
      KH_1; KH domain
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    6. NM_001360490.1NP_001347419.1  heterogeneous nuclear ribonucleoprotein K isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC154437
      Conserved Domains (3) summary
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam00013
      Location:389453
      KH_1; KH domain
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    7. NM_001360491.1NP_001347420.1  heterogeneous nuclear ribonucleoprotein K isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC154437
      Conserved Domains (3) summary
      cd00105
      Location:384447
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    8. NM_001360493.1NP_001347422.1  heterogeneous nuclear ribonucleoprotein K isoform 6

      Status: REVIEWED

      Source sequence(s)
      AC154437
      Conserved Domains (3) summary
      cd00105
      Location:384447
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    9. NM_001360494.1NP_001347423.1  heterogeneous nuclear ribonucleoprotein K isoform 3

      Status: REVIEWED

      Source sequence(s)
      AC154437
      Conserved Domains (3) summary
      cd00105
      Location:365428
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:122186
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    10. NM_001360495.1NP_001347424.1  heterogeneous nuclear ribonucleoprotein K isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC154437
      Conserved Domains (3) summary
      cd02396
      Location:122186
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam00013
      Location:365429
      KH_1; KH domain
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    11. NM_025279.3NP_079555.1  heterogeneous nuclear ribonucleoprotein K isoform 2

      See identical proteins and their annotated locations for NP_079555.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) uses an alternative splice site in the 3' terminal exon, which results in a frameshift, compared to variant 1. It encodes isoform 2 which has a distinct and shorter C-terminus compared to isoform 1.
      Source sequence(s)
      AK011428, AV367088, BC089328, BE993983
      Consensus CDS
      CCDS49283.1
      UniProtKB/Swiss-Prot
      P61979
      UniProtKB/TrEMBL
      Q5FWJ5
      Related
      ENSMUSP00000039269.7, OTTMUSP00000050779, ENSMUST00000043269.13, OTTMUST00000092043
      Conserved Domains (3) summary
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam00013
      Location:389453
      KH_1; KH domain
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain

    RNA

    1. NR_153501.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC154437
    2. NR_153502.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC154437
    3. NR_153503.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC154437
    4. NR_153504.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC154437

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      58391132..58403343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315396.1XP_017170885.1  heterogeneous nuclear ribonucleoprotein K isoform X4

      UniProtKB/Swiss-Prot
      P61979
      Conserved Domains (3) summary
      cd02396
      Location:122186
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam00013
      Location:365429
      KH_1; KH domain
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    2. XM_017315395.1XP_017170884.1  heterogeneous nuclear ribonucleoprotein K isoform X2

      UniProtKB/Swiss-Prot
      P61979
      Related
      ENSMUSP00000135833.1, OTTMUSP00000061592, ENSMUST00000177497.7, OTTMUST00000110425
      Conserved Domains (3) summary
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam00013
      Location:389453
      KH_1; KH domain
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    3. XM_006517104.2XP_006517167.1  heterogeneous nuclear ribonucleoprotein K isoform X1

      See identical proteins and their annotated locations for XP_006517167.1

      UniProtKB/Swiss-Prot
      P61979
      UniProtKB/TrEMBL
      Q5FWJ5
      Conserved Domains (3) summary
      cd00105
      Location:389452
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    4. XM_006517103.3XP_006517166.1  heterogeneous nuclear ribonucleoprotein K isoform X1

      See identical proteins and their annotated locations for XP_006517166.1

      UniProtKB/Swiss-Prot
      P61979
      UniProtKB/TrEMBL
      Q5FWJ5
      Conserved Domains (3) summary
      cd00105
      Location:389452
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:146210
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
    5. XM_006517106.3XP_006517169.1  heterogeneous nuclear ribonucleoprotein K isoform X3

      UniProtKB/TrEMBL
      B2M1R6
      Conserved Domains (3) summary
      cd00105
      Location:365428
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:122186
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
      pfam08067
      Location:1343
      ROKNT; ROKNT (NUC014) domain
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