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    Hmg20b high mobility group 20B [ Mus musculus (house mouse) ]

    Gene ID: 15353, updated on 23-Jun-2021

    Summary

    Official Symbol
    Hmg20bprovided by MGI
    Official Full Name
    high mobility group 20Bprovided by MGI
    Primary source
    MGI:MGI:1341190
    See related
    Ensembl:ENSMUSG00000020232
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BRAF; Smar; Hmgx2; BRAF35; Hmgxb2; AW610687; Smarce1r
    Expression
    Ubiquitous expression in duodenum adult (RPKM 74.1), adrenal adult (RPKM 70.0) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Hmg20b in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (81181880..81186777, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (81346046..81350943, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (80808791..80813202, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene thromboxane A2 receptor Neighboring gene GIPC PDZ domain containing family, member 3 Neighboring gene major facilitator superfamily domain containing 12 Neighboring gene RIKEN cDNA 4930404N11 gene Neighboring gene fizzy and cell division cycle 20 related 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables four-way junction DNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of BRCA2-BRAF35 complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in condensed nuclear chromosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
    Names
    BRCA2-associated factor 35
    HMG box-containing protein 20B
    SMARCE1-related protein
    high mobility group 20 B
    high mobility group protein 20 B
    structural DNA-binding protein BRAF35

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163165.1NP_001156637.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

      See identical proteins and their annotated locations for NP_001156637.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      AK155615, AK155890, BE956207
      Consensus CDS
      CCDS24055.1
      UniProtKB/Swiss-Prot
      Q9Z104
      UniProtKB/TrEMBL
      Q3U1L0, Q3U1Z7
      Related
      ENSMUSP00000100961.3, ENSMUST00000105324.9
      Conserved Domains (1) summary
      cd01390
      Location:70134
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    2. NM_001163166.1NP_001156638.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

      See identical proteins and their annotated locations for NP_001156638.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      AK153816, BE956207
      Consensus CDS
      CCDS24055.1
      UniProtKB/Swiss-Prot
      Q9Z104
      UniProtKB/TrEMBL
      Q3U1L0
      Related
      ENSMUSP00000100960.2, ENSMUST00000105323.8
      Conserved Domains (1) summary
      cd01390
      Location:70134
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    3. NM_010440.3NP_034570.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

      See identical proteins and their annotated locations for NP_034570.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
      Source sequence(s)
      AC155937, AK155890, BE956207
      Consensus CDS
      CCDS24055.1
      UniProtKB/Swiss-Prot
      Q9Z104
      UniProtKB/TrEMBL
      Q3U1L0
      Related
      ENSMUSP00000020454.5, ENSMUST00000020454.11
      Conserved Domains (1) summary
      cd01390
      Location:70134
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      81181880..81186777 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155645.1XP_036011538.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related isoform X2

      Conserved Domains (2) summary
      PRK10246
      Location:57167
      PRK10246; exonuclease subunit SbcC; Provisional
      smart00935
      Location:2690
      OmpH; Outer membrane protein (OmpH-like)
    2. XM_006513248.3XP_006513311.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related isoform X1

      See identical proteins and their annotated locations for XP_006513311.1

      Conserved Domains (3) summary
      smart00935
      Location:190254
      OmpH; Outer membrane protein (OmpH-like)
      cd01390
      Location:70134
      HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...
      pfam15258
      Location:314400
      FAM222A; Protein family of FAM222A
    3. XM_036155646.1XP_036011539.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related isoform X2

      Conserved Domains (2) summary
      PRK10246
      Location:57167
      PRK10246; exonuclease subunit SbcC; Provisional
      smart00935
      Location:2690
      OmpH; Outer membrane protein (OmpH-like)
    4. XM_006513249.5XP_006513312.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related isoform X1

      See identical proteins and their annotated locations for XP_006513312.1

      Conserved Domains (3) summary
      smart00935
      Location:190254
      OmpH; Outer membrane protein (OmpH-like)
      cd01390
      Location:70134
      HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...
      pfam15258
      Location:314400
      FAM222A; Protein family of FAM222A
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